Trichlormethiazide and Hypothyroidism - a phase IV clinical study of FDA data

Summary:

Hypothyroidism is reported as a side effect among people who take Trichlormethiazide (trichlormethiazide), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lidoderm, and have Breast cancer.

The phase IV clinical study analyzes which people have Hypothyroidism when taking Trichlormethiazide. It is created by eHealthMe based on reports of 2,613 people who have side effects when taking Trichlormethiazide from the FDA, and is updated regularly.

What is Trichlormethiazide?

Trichlormethiazide has active ingredients of trichlormethiazide. eHealthMe is studying from 2,613 Trichlormethiazide users. Check the latest studies of Trichlormethiazide.

What is Hypothyroidism?

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development) is found to be associated with 1,614 drugs and 2,598 conditions by eHealthMe. Check the latest studies of Hypothyroidism.



On Jul, 10, 2026

2,613 people reported to have side effects when taking Trichlormethiazide.
Among them, 22 people (0.84%) have Hypothyroidism.

Could Trichlormethiazide cause Hypothyroidism?

Among these 22 people:

How long have people been on Trichlormethiazide when they have Hypothyroidism? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypothyroidism when taking Trichlormethiazide? *

  • female: 90.91 %
  • male: 9.09 %

What is the age of people who have Hypothyroidism when taking Trichlormethiazide? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 47.62 %
  • 50-59: 0.0 %
  • 60+: 52.38 %

What are other drugs people take besides Trichlormethiazide? *

  1. Zometa: 11 people, 50.00%
  2. Faslodex: 11 people, 50.00%
  3. Prilosec: 11 people, 50.00%
  4. Fish Oil: 11 people, 50.00%
  5. Grape Seed: 11 people, 50.00%
  6. Peridex: 11 people, 50.00%
  7. Hydroxyzine: 11 people, 50.00%
  8. Lantus: 11 people, 50.00%
  9. Levofloxacin: 11 people, 50.00%
  10. Lidoderm: 11 people, 50.00%

What are other side effects people have besides Hypothyroidism? *

  1. Diarrhea: 16 people, 72.73%
  2. High Blood Pressure: 13 people, 59.09%
  3. Pneumonia: 12 people, 54.55%
  4. Weight Increased: 11 people, 50.00%
  5. General Physical Health Deterioration (weak health status): 11 people, 50.00%
  6. Osteonecrosis Of Jaw (death of bone of jaw): 11 people, 50.00%
  7. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 11 people, 50.00%
  8. Muscle Spasms (muscle contraction): 11 people, 50.00%
  9. Metastases To Liver (cancer spreads to liver): 11 people, 50.00%
  10. Memory Loss: 11 people, 50.00%

What are the existing conditions these people have? *

  1. Quit Smoking: 11 people, 50.00%
  2. Breast Cancer: 11 people, 50.00%
  3. Bone Neoplasm Malignant (cancer of bone): 10 people, 45.45%
  4. Bone Loss: 7 people, 31.82%
  5. High Blood Pressure: 6 people, 27.27%
  6. Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 4 people, 18.18%
  7. Bone Density Decreased: 4 people, 18.18%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 18.18%
  9. Hepatic Neoplasm Malignant (liver cancer): 3 people, 13.64%
  10. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 13.64%

* Approximation only. Some reports may have incomplete information.

Do you take Trichlormethiazide and have Hypothyroidism?

- Check whether Hypothyroidism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Trichlormethiazide:

Hypothyroidism treatments and more:

How severe was Hypothyroidism and when was it recovered:

Expand to all the drugs that have ingredients of trichlormethiazide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Trichlormethiazide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypothyroidism:

Browse all the conditions that are associated with Hypothyroidism:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on trichlormethiazide (the active ingredients of Trichlormethiazide) and Trichlormethiazide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: