Tridil and Death - a phase IV clinical study of FDA data

Summary:

Death is reported as a side effect among people who take Tridil (nitroglycerin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Trasylol, and have Heart attack.

The study is created by eHealthMe based on reports of 170 people who have side effects when taking Tridil from the FDA, and is updated regularly.

What is Tridil?

Tridil has active ingredients of nitroglycerin. eHealthMe is studying from 174 Tridil users. Check the latest studies of Tridil.



On Jul, 17, 2026

170 people reported to have side effects when taking Tridil.
Among them, 31 people (18.24%) died.

Could Tridil cause Death?

Among these 31 people:

How long have people been on Tridil when they died? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who died when taking Tridil? *

  • female: 20 %
  • male: 80 %

What is the age of people who died when taking Tridil? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 17.24 %
  • 50-59: 20.69 %
  • 60+: 62.07 %

What are other drugs people take besides Tridil? *

  1. Heparin: 21 people, 67.74%
  2. Trasylol: 21 people, 67.74%
  3. Versed: 13 people, 41.94%
  4. Lasix: 12 people, 38.71%
  5. Nitroglycerin: 10 people, 32.26%
  6. Protamine Sulfate: 9 people, 29.03%
  7. Zocor: 9 people, 29.03%
  8. Vancomycin: 8 people, 25.81%
  9. Ancef: 8 people, 25.81%
  10. Coreg: 7 people, 22.58%

What are other side effects people have before they died? *

  1. Injury: 21 people, 67.74%
  2. Pain: 21 people, 67.74%
  3. Stress And Anxiety: 20 people, 64.52%
  4. Acute Kidney Failure: 20 people, 64.52%
  5. Fear: 18 people, 58.06%
  6. Anhedonia (inability to experience pleasure from activities usually found enjoyable): 16 people, 51.61%
  7. Renal Impairment (severely reduced kidney function): 15 people, 48.39%
  8. Renal Injury (kidney injury): 15 people, 48.39%
  9. Emotional Distress: 14 people, 45.16%
  10. Multi-Organ Failure (multisystem organ failure): 13 people, 41.94%

What are the existing conditions these people have? *

  1. Acute Myocardial Infarction (acute heart attack): 3 people, 9.68%
  2. Ankylosing Spondylitis (type of arthritis affecting the spine): 3 people, 9.68%
  3. Heart Attack: 3 people, 9.68%
  4. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 6.45%
  5. High Blood Pressure: 2 people, 6.45%
  6. High Blood Cholesterol: 2 people, 6.45%
  7. Gastrointestinal Neoplasm (cancer tumour of digestive tract): 2 people, 6.45%
  8. Diabetes: 2 people, 6.45%
  9. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 6.45%
  10. Cardiac Failure: 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tridil:

Expand to all the drugs that have ingredients of nitroglycerin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tridil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Death:

Browse all the conditions that are associated with Death:

  • Death (3,686 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nitroglycerin (the active ingredients of Tridil) and Tridil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: