Trileptal and Complex partial seizures - a phase IV clinical study of FDA data

Summary:

Complex partial seizures is reported as a side effect among people who take Trileptal (oxcarbazepine), especially for people who are female, 10-19 old, have been taking the drug for < 1 month also take Keppra, and have Convulsion.

The phase IV clinical study analyzes which people have Complex partial seizures when taking Trileptal. It is created by eHealthMe based on reports of 22,012 people who have side effects when taking Trileptal from the FDA, and is updated regularly.

What is Trileptal?

Trileptal has active ingredients of oxcarbazepine. It is often used in bipolar disorder. eHealthMe is studying from 23,558 Trileptal users. Check the latest studies of Trileptal.

What is Complex partial seizures?

Complex partial seizures (epileptic seizure) is found to be associated with 216 drugs and 440 conditions by eHealthMe. Check the latest studies of Complex partial seizures.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 17, 2026

22,012 people reported to have side effects when taking Trileptal.
Among them, 53 people (0.24%) have Complex partial seizures.

Could Trileptal cause Complex partial seizures?

Among these 53 people:

How long have people been on Trileptal when they have Complex partial seizures? *

What is the gender of people who have Complex partial seizures when taking Trileptal? *

female: 52.83 %
male: 47.17 %

What is the age of people who have Complex partial seizures when taking Trileptal? *

What are other drugs people take besides Trileptal? *

What are other side effects people have besides Complex partial seizures? *

Memory Loss: 11 people, 20.75%
Headache (pain in head): 10 people, 18.87%
Drowsiness: 8 people, 15.09%
Depression: 8 people, 15.09%
Fall: 7 people, 13.21%
Drug Ineffective: 7 people, 13.21%
Stress And Anxiety: 6 people, 11.32%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 5 people, 9.43%
Fatigue (feeling of tiredness): 5 people, 9.43%
Tremor (trembling or shaking movements in one or more parts of your body): 5 people, 9.43%

What are the existing conditions these people have? *

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 8 people, 15.09%
Birth Control: 4 people, 7.55%
Astrocytoma, Low Grade (low grade tumour of the brain that originate in a particular kind of glial-cells): 3 people, 5.66%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 5.66%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 3.77%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 3.77%
Tonic Clonic Movements (generalized seizure that affects the entire brain): 2 people, 3.77%
Tuberous Sclerosis (a rare genetic disease that causes benign tumours to grow in the brain and other organs): 1 person, 1.89%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 1.89%
Asthma: 1 person, 1.89%

* Approximation only. Some reports may have incomplete information.

Do you take Trileptal and have Complex partial seizures?

- Check whether Complex partial seizures is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Trileptal:

Trileptal (23,558 reports)

Browse all side effects of Trileptal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Complex partial seizures:

Complex partial seizures (216 drugs)

Browse all the conditions that are associated with Complex partial seizures:

Complex partial seizures (440 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on oxcarbazepine (the active ingredients of Trileptal) and Trileptal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.