Trileptal and Excessive eye blinking - a phase IV clinical study of FDA data

Summary:

Excessive eye blinking is reported as a side effect among people who take Trileptal (oxcarbazepine), especially for people who are male, 10-19 old, have been taking the drug for < 1 month also take Tegretol, and have Convulsion.

The phase IV clinical study analyzes which people have Excessive eye blinking when taking Trileptal. It is created by eHealthMe based on reports of 22,012 people who have side effects when taking Trileptal from the FDA, and is updated regularly.

What is Trileptal?

Trileptal has active ingredients of oxcarbazepine. It is often used in bipolar disorder. eHealthMe is studying from 23,558 Trileptal users. Check the latest studies of Trileptal.

What is Excessive eye blinking?

Excessive eye blinking (excessive blinking is dry eyes) is found to be associated with 209 drugs and 409 conditions by eHealthMe. Check the latest studies of Excessive eye blinking.



On Jul, 15, 2026

22,012 people reported to have side effects when taking Trileptal.
Among them, 19 people (0.09%) have Excessive eye blinking.

Could Trileptal cause Excessive eye blinking?

Among these 19 people:

How long have people been on Trileptal when they have Excessive eye blinking? *

  • < 1 month: 50 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Excessive eye blinking when taking Trileptal? *

  • female: 31.58 %
  • male: 68.42 %

What is the age of people who have Excessive eye blinking when taking Trileptal? *

  • 0-1: 0.0 %
  • 2-9: 38.46 %
  • 10-19: 46.15 %
  • 20-29: 7.69 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 7.69 %
  • 60+: 0.0 %

What are other drugs people take besides Trileptal? *

  1. Tegretol: 4 people, 21.05%
  2. Prilosec: 3 people, 15.79%
  3. Lamictal: 2 people, 10.53%
  4. Travatan: 2 people, 10.53%
  5. Dexamethasone: 2 people, 10.53%
  6. Nasacort: 2 people, 10.53%
  7. Protonix: 2 people, 10.53%
  8. Metoclopramide: 2 people, 10.53%
  9. Bextra: 2 people, 10.53%
  10. Albuterol: 2 people, 10.53%

What are other side effects people have besides Excessive eye blinking? *

  1. Fatigue (feeling of tiredness): 8 people, 42.11%
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 7 people, 36.84%
  3. Drowsiness: 4 people, 21.05%
  4. Acute Upper Airway Obstruction (blockage occurs in the upper airway): 4 people, 21.05%
  5. Muscle Twitching: 4 people, 21.05%
  6. Psychomotor Hyperactivity (feelings of extreme restlessness): 4 people, 21.05%
  7. Swallowing Difficulty: 4 people, 21.05%
  8. Jaw Disorder (jaw disease): 4 people, 21.05%
  9. Dizziness: 4 people, 21.05%
  10. Salivary Hypersecretion (excess saliva secretion): 4 people, 21.05%

What are the existing conditions these people have? *

  1. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 7 people, 36.84%
  2. Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 2 people, 10.53%
  3. Seasonal Allergy (allergic condition due to certain season): 1 person, 5.26%
  4. Nausea (feeling of having an urge to vomit): 1 person, 5.26%
  5. Intraocular Pressure Test Abnormal: 1 person, 5.26%
  6. High Blood Pressure: 1 person, 5.26%
  7. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 1 person, 5.26%
  8. Cerebral Disorder (brain disease): 1 person, 5.26%
  9. Benign Rolandic Epilepsy (benign childhood epilepsy with centrotemporal spikes): 1 person, 5.26%
  10. Affective Disorder (mental disorder): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Trileptal and have Excessive eye blinking?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Trileptal:

Excessive eye blinking treatments and more:

How severe was Excessive eye blinking and when was it recovered:

Expand to all the drugs that have ingredients of oxcarbazepine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Trileptal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Excessive eye blinking:

Browse all the conditions that are associated with Excessive eye blinking:


How the study uses the data?

The study uses data from the FDA. It is based on oxcarbazepine (the active ingredients of Trileptal) and Trileptal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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