Trileptal and Formication - a phase IV clinical study of FDA data

Summary:

Formication is reported as a side effect among people who take Trileptal (oxcarbazepine), especially for people who are female, 40-49 old, have been taking the drug for 2 - 5 years also take Seroquel, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Formication when taking Trileptal. It is created by eHealthMe based on reports of 22,012 people who have side effects when taking Trileptal from the FDA, and is updated regularly.

What is Trileptal?

Trileptal has active ingredients of oxcarbazepine. It is often used in bipolar disorder. eHealthMe is studying from 23,557 Trileptal users. Check the latest studies of Trileptal.

What is Formication?

Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin) is found to be associated with 558 drugs and 917 conditions by eHealthMe. Check the latest studies of Formication.

On Jan, 08, 2026

22,012 people reported to have side effects when taking Trileptal.
Among them, 30 people (0.14%) have Formication.

Among these 30 people:

How long have people been on Trileptal when they have Formication? *

What is the gender of people who have Formication when taking Trileptal? *

female: 86.21 %
male: 13.79 %

What is the age of people who have Formication when taking Trileptal? *

What are other drugs people take besides Trileptal? *

Seroquel: 10 people, 33.33%
Diazepam: 6 people, 20.00%
Zoloft: 5 people, 16.67%
Neurontin: 5 people, 16.67%
Rebif: 5 people, 16.67%
Clonazepam: 4 people, 13.33%
Citalopram Hydrobromide: 4 people, 13.33%
Lyrica: 3 people, 10.00%
Singulair: 3 people, 10.00%
Synthroid: 3 people, 10.00%

What are other side effects people have besides Formication? *

Depression: 14 people, 46.67%
Agitation (state of anxiety or nervous excitement): 13 people, 43.33%
Insomnia (sleeplessness): 13 people, 43.33%
Dizziness: 10 people, 33.33%
Tremor (trembling or shaking movements in one or more parts of your body): 10 people, 33.33%
Stress And Anxiety: 8 people, 26.67%
Suicidal Ideation: 7 people, 23.33%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 7 people, 23.33%
Dry Mouth: 7 people, 23.33%
Drowsiness: 7 people, 23.33%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 20.00%
Depression: 5 people, 16.67%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 13.33%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 10.00%
Asthma: 3 people, 10.00%
Growth Hormone Deficiency: 3 people, 10.00%
Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 3 people, 10.00%
Adrenal Insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids): 3 people, 10.00%
Quit Smoking: 3 people, 10.00%
Post Herpetic Neuralgia (neuralgia caused by the varicella zoster virus): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Trileptal and have Formication?

- Check whether Formication is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Trileptal:

Trileptal (23,557 reports)

Formication treatments and more:

Formication (8,246 reports)

Browse all side effects of Trileptal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Formication:

Formication (558 drugs)

Browse all the conditions that are associated with Formication:

Formication (917 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on oxcarbazepine (the active ingredients of Trileptal) and Trileptal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.