Trintellix and Hyponatraemia aggravated - a phase IV clinical study of FDA data

Summary:

Hyponatraemia aggravated is reported as a side effect among people who take Trintellix (vortioxetine hydrobromide), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Synthroid, and have Stress and anxiety.

The phase IV clinical study analyzes which people have Hyponatraemia aggravated when taking Trintellix. It is created by eHealthMe based on reports of 12,454 people who have side effects when taking Trintellix from the FDA, and is updated regularly.

What is Trintellix?

Trintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 13,067 Trintellix users. Check the latest studies of Trintellix.

What is Hyponatraemia aggravated?

Hyponatraemia aggravated (abnormally low concentrations of sodium ions in the circulating blood) is found to be associated with 1,469 drugs and 531 conditions by eHealthMe. Check the latest studies of Hyponatraemia aggravated.



On Apr, 20, 2026

12,454 people reported to have side effects when taking Trintellix.
Among them, 52 people (0.42%) have Hyponatraemia aggravated.

Could Trintellix cause Hyponatraemia aggravated?

Among these 52 people:

How long have people been on Trintellix when they have Hyponatraemia aggravated? *

What is the gender of people who have Hyponatraemia aggravated when taking Trintellix? *

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What is the age of people who have Hyponatraemia aggravated when taking Trintellix? *

What are other drugs people take besides Trintellix? *

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What are other side effects people have besides Hyponatraemia aggravated? *

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What are the existing conditions these people have? *

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* Approximation only. Some reports may have incomplete information.

Do you take Trintellix and have Hyponatraemia aggravated?

- Check whether Hyponatraemia aggravated is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Trintellix:

Hyponatraemia aggravated treatments and more:

How severe was Hyponatraemia aggravated and when was it recovered:

Expand to all the drugs that have ingredients of vortioxetine hydrobromide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Trintellix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyponatraemia aggravated:

Browse all the conditions that are associated with Hyponatraemia aggravated:


How the study uses the data?

The study uses data from the FDA. It is based on vortioxetine hydrobromide (the active ingredients of Trintellix) and Trintellix (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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