Triphasil-21 and Muscle aches - a phase IV clinical study of FDA data

Summary:

Muscle aches is reported as a side effect among people who take Triphasil-21 (ethinyl estradiol; levonorgestrel), especially for people who are female, 30-39 old, have been taking the drug for 2 - 5 years also take Ibuprofen, and have Eczema.

The phase IV clinical study analyzes which people have Muscle aches when taking Triphasil-21. It is created by eHealthMe based on reports of 530 people who have side effects when taking Triphasil-21 from the FDA, and is updated regularly.

What is Triphasil-21?

Triphasil-21 has active ingredients of ethinyl estradiol; levonorgestrel. eHealthMe is studying from 534 Triphasil-21 users. Check the latest studies of Triphasil-21.

What is Muscle aches?

Muscle aches (muscle pain) is found to be associated with 2,723 drugs and 3,745 conditions by eHealthMe. Check the latest studies of Muscle aches.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

530 people reported to have side effects when taking Triphasil-21.
Among them, 13 people (2.45%) have Muscle aches.

Among these 13 people:

How long have people been on Triphasil-21 when they have Muscle aches? *

What is the gender of people who have Muscle aches when taking Triphasil-21? *

female: 100 %
male: 0.0 %

What is the age of people who have Muscle aches when taking Triphasil-21? *

What are other drugs people take besides Triphasil-21? *

What are other side effects people have besides Muscle aches? *

Dizziness: 10 people, 76.92%
Headache (pain in head): 9 people, 69.23%
Asthma: 8 people, 61.54%
Fatigue (feeling of tiredness): 8 people, 61.54%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 7 people, 53.85%
Memory Loss: 7 people, 53.85%
Nausea (feeling of having an urge to vomit): 7 people, 53.85%
Constipation: 7 people, 53.85%
Weakness: 6 people, 46.15%
Bone Pain: 6 people, 46.15%

What are the existing conditions these people have? *

Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 5 people, 38.46%
Stress And Anxiety: 3 people, 23.08%
Sleep Disorder: 3 people, 23.08%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 15.38%
Depression: 2 people, 15.38%
Birth Control: 1 person, 7.69%
Acne (skin problems that cause pimples): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Triphasil-21 and have Muscle aches?

- Check whether Muscle aches is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Triphasil-21:

Triphasil-21 (534 reports)

Muscle aches treatments and more:

Muscle aches (219,259 reports)

How severe was Muscle aches and when was it recovered:

Muscle aches in Triphasil-21

Expand to all the drugs that have ingredients of ethinyl estradiol; levonorgestrel:

Muscle aches and drugs with ingredients of ethinyl estradiol; levonorgestrel (215 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Triphasil-21:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle aches:

Muscle aches (2,723 drugs)

Browse all the conditions that are associated with Muscle aches:

Muscle aches (3,745 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ethinyl estradiol; levonorgestrel (the active ingredients of Triphasil-21) and Triphasil-21 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.