Trizivir and Insomnia exacerbated - a phase IV clinical study of FDA data

Summary:

Insomnia exacerbated is reported as a side effect among people who take Trizivir (abacavir sulfate; lamivudine; zidovudine), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Sustiva, and have Depression.

The phase IV clinical study analyzes which people have Insomnia exacerbated when taking Trizivir. It is created by eHealthMe based on reports of 2,801 people who have side effects when taking Trizivir from the FDA, and is updated regularly.

What is Trizivir?

Trizivir has active ingredients of abacavir sulfate; lamivudine; zidovudine. It is often used in hiv infection. eHealthMe is studying from 2,813 Trizivir users. Check the latest studies of Trizivir.

What is Insomnia exacerbated?

Insomnia exacerbated (severe sleeplessness) is found to be associated with 2,690 drugs and 976 conditions by eHealthMe. Check the latest studies of Insomnia exacerbated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

2,801 people reported to have side effects when taking Trizivir.
Among them, 36 people (1.29%) have Insomnia exacerbated.

Could Trizivir cause Insomnia exacerbated?

Among these 36 people:

How long have people been on Trizivir when they have Insomnia exacerbated? *

What is the gender of people who have Insomnia exacerbated when taking Trizivir? *

female: 5.71 %
male: 94.29 %

What is the age of people who have Insomnia exacerbated when taking Trizivir? *

What are other drugs people take besides Trizivir? *

What are other side effects people have besides Insomnia exacerbated? *

Stress And Anxiety: 18 people, 50.00%
Depression: 15 people, 41.67%
Nausea (feeling of having an urge to vomit): 15 people, 41.67%
Pain: 13 people, 36.11%
Emotional Distress: 11 people, 30.56%
Confusional State: 8 people, 22.22%
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 8 people, 22.22%
Fever: 8 people, 22.22%
Fatigue (feeling of tiredness): 7 people, 19.44%
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 7 people, 19.44%

What are the existing conditions these people have? *

Depression: 6 people, 16.67%
High Blood Pressure: 4 people, 11.11%
Erection Problems: 4 people, 11.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 11.11%
Rashes (redness): 3 people, 8.33%
Pain: 3 people, 8.33%
Dizziness: 2 people, 5.56%
Bone Density Decreased: 2 people, 5.56%
Blood Testosterone Decreased: 2 people, 5.56%
Tooth Abscess (pus formation in tooth): 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Trizivir and have Insomnia exacerbated?

- Check whether Insomnia exacerbated is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Trizivir:

Trizivir (2,813 reports)

Insomnia exacerbated treatments and more:

Insomnia exacerbated (337 reports)

How severe was Insomnia exacerbated and when was it recovered:

Insomnia exacerbated in Trizivir

Expand to all the drugs that have ingredients of abacavir sulfate; lamivudine; zidovudine:

Insomnia exacerbated and drugs with ingredients of abacavir sulfate; lamivudine; zidovudine

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Trizivir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Insomnia exacerbated:

Insomnia exacerbated (2,690 drugs)

Browse all the conditions that are associated with Insomnia exacerbated:

Insomnia exacerbated (976 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on abacavir sulfate; lamivudine; zidovudine (the active ingredients of Trizivir) and Trizivir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.