Truvada and Bone loss - a phase IV clinical study of FDA data

Summary:

Bone loss is reported as a side effect among people who take Truvada (emtricitabine; tenofovir disoproxil fumarate), especially for people who are male, 50-59 old, have been taking the drug for 5 - 10 years also take Viread, and have Acquired immunodeficiency syndrome.

The phase IV clinical study analyzes which people have Bone loss when taking Truvada. It is created by eHealthMe based on reports of 75,548 people who have side effects when taking Truvada from the FDA, and is updated regularly.

What is Truvada?

Truvada has active ingredients of emtricitabine; tenofovir disoproxil fumarate. It is often used in hiv infection. eHealthMe is studying from 76,246 Truvada users. Check the latest studies of Truvada.

What is Bone loss?

Bone loss is found to be associated with 695 drugs and 559 conditions by eHealthMe. Check the latest studies of Bone loss.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

75,548 people reported to have side effects when taking Truvada.
Among them, 16,065 people (21.26%) have Bone loss.

Among these 16,065 people:

* Approximation only. Some reports may have incomplete information.

Do you take Truvada and have Bone loss?

- Check whether Bone loss is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Truvada:

Truvada (76,246 reports)

Bone loss treatments and more:

Bone loss (27,142 reports)

How severe was Bone loss and when was it recovered:

Bone loss in Truvada

Expand to all the drugs that have ingredients of emtricitabine; tenofovir disoproxil fumarate:

Bone loss and drugs with ingredients of emtricitabine; tenofovir disoproxil fumarate (16,067 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Truvada:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bone loss:

Bone loss (695 drugs)

Browse all the conditions that are associated with Bone loss:

Bone loss (559 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on emtricitabine; tenofovir disoproxil fumarate (the active ingredients of Truvada) and Truvada (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.