Truvada and Lumbar spinal stenosis - a phase IV clinical study of FDA data

Summary:

Lumbar spinal stenosis is reported as a side effect among people who take Truvada (emtricitabine; tenofovir disoproxil fumarate), especially for people who are male, 50-59 old, have been taking the drug for 5 - 10 years also take Viread, and have Acquired immunodeficiency syndrome.

The phase IV clinical study analyzes which people have Lumbar spinal stenosis when taking Truvada. It is created by eHealthMe based on reports of 75,548 people who have side effects when taking Truvada from the FDA, and is updated regularly.

What is Truvada?

Truvada has active ingredients of emtricitabine; tenofovir disoproxil fumarate. It is often used in hiv infection. eHealthMe is studying from 76,246 Truvada users. Check the latest studies of Truvada.

What is Lumbar spinal stenosis?

Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone) is found to be associated with 763 drugs and 694 conditions by eHealthMe. Check the latest studies of Lumbar spinal stenosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

75,548 people reported to have side effects when taking Truvada.
Among them, 44 people (0.06%) have Lumbar spinal stenosis.

Could Truvada cause Lumbar spinal stenosis?

Among these 44 people:

How long have people been on Truvada when they have Lumbar spinal stenosis? *

What is the gender of people who have Lumbar spinal stenosis when taking Truvada? *

female: 21.43 %
male: 78.57 %

What is the age of people who have Lumbar spinal stenosis when taking Truvada? *

What are other drugs people take besides Truvada? *

What are other side effects people have besides Lumbar spinal stenosis? *

Bone Density Decreased: 35 people, 79.55%
Emotional Distress: 31 people, 70.45%
Pain: 31 people, 70.45%
Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 27 people, 61.36%
Osteopenia (a condition where bone mineral density is lower than normal): 24 people, 54.55%
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 23 people, 52.27%
Stress And Anxiety: 23 people, 52.27%
Osteoporosis (bones weak and more likely to break): 21 people, 47.73%
Bone Loss: 21 people, 47.73%
Tooth Loss: 16 people, 36.36%

What are the existing conditions these people have? *

Acquired Immunodeficiency Syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv)): 6 people, 13.64%
Hepatitis B: 4 people, 9.09%
Urinary Tract Infection: 1 person, 2.27%
Maternal Therapy To Enhance Foetal Lung Maturity: 1 person, 2.27%
Ill-Defined Disorder: 1 person, 2.27%
Acne (skin problems that cause pimples): 1 person, 2.27%

* Approximation only. Some reports may have incomplete information.

Do you take Truvada and have Lumbar spinal stenosis?

- Check whether Lumbar spinal stenosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Truvada:

Truvada (76,246 reports)

Lumbar spinal stenosis treatments and more:

Lumbar spinal stenosis (6,965 reports)

How severe was Lumbar spinal stenosis and when was it recovered:

Lumbar spinal stenosis in Truvada

Expand to all the drugs that have ingredients of emtricitabine; tenofovir disoproxil fumarate:

Lumbar spinal stenosis and drugs with ingredients of emtricitabine; tenofovir disoproxil fumarate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Truvada:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lumbar spinal stenosis:

Lumbar spinal stenosis (763 drugs)

Browse all the conditions that are associated with Lumbar spinal stenosis:

Lumbar spinal stenosis (694 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on emtricitabine; tenofovir disoproxil fumarate (the active ingredients of Truvada) and Truvada (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.