Truxima and Knee joint replacement - a phase IV clinical study of FDA data

Summary:

Knee joint replacement is reported as a side effect among people who take Truxima (rituximab-abbs), especially for people who are female, 40-49 old, have been taking the drug for 6 - 12 months also take Acetaminophen, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Knee joint replacement when taking Truxima. It is created by eHealthMe based on reports of 4,063 people who have side effects when taking Truxima from the FDA, and is updated regularly.

What is Truxima?

Truxima has active ingredients of rituximab-abbs. eHealthMe is studying from 4,063 Truxima users. Check the latest studies of Truxima.

What is Knee joint replacement?

Knee joint replacement is found to be associated with 953 drugs and 1,228 conditions by eHealthMe. Check the latest studies of Knee joint replacement.

On Jul, 06, 2026

4,063 people reported to have side effects when taking Truxima.
Among them, 39 people (0.96%) have Knee joint replacement.

Could Truxima cause Knee joint replacement?

Among these 39 people:

How long have people been on Truxima when they have Knee joint replacement? *

What is the gender of people who have Knee joint replacement when taking Truxima? *

female: 100 %
male: 0.0 %

What is the age of people who have Knee joint replacement when taking Truxima? *

What are other drugs people take besides Truxima? *

What are other side effects people have besides Knee joint replacement? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 35 people, 89.74%
Rashes (redness): 34 people, 87.18%
Drug Ineffective: 34 people, 87.18%
Abdominal Discomfort: 33 people, 84.62%
Helicobacter Infection (helicobacter pylori (h. pylori) infects stomach): 33 people, 84.62%
Pain: 33 people, 84.62%
Hypersensitivity: 33 people, 84.62%
Hepatic Enzyme Increased: 33 people, 84.62%
Hair Loss: 33 people, 84.62%
Discomfort: 33 people, 84.62%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 39 people, 100.00%
Stress And Anxiety: 11 people, 28.21%
Psoriasis (immune-mediated disease that affects the skin): 11 people, 28.21%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 9 people, 23.08%
Fever: 8 people, 20.51%
Pain: 5 people, 12.82%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 5 people, 12.82%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 4 people, 10.26%
Ankylosing Spondylitis (type of arthritis affecting the spine): 4 people, 10.26%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 3 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Truxima and have Knee joint replacement?

- Check whether Knee joint replacement is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Truxima:

Truxima (4,063 reports)

Browse all side effects of Truxima:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Knee joint replacement:

Knee joint replacement (953 drugs)

Browse all the conditions that are associated with Knee joint replacement:

Knee joint replacement (1,228 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on rituximab-abbs (the active ingredients of Truxima) and Truxima (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.