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Tukysa and Nosebleed - a phase IV clinical study of FDA data

Summary:

Nosebleed is reported as a side effect among people who take Tukysa (tucatinib), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Capecitabine, and have Breast cancer female.

The phase IV clinical study analyzes which people have Nosebleed when taking Tukysa. It is created by eHealthMe based on reports of 3,215 people who have side effects when taking Tukysa from the FDA, and is updated regularly.

What is Tukysa?

Tukysa has active ingredients of tucatinib. eHealthMe is studying from 3,216 Tukysa users. Check the latest studies of Tukysa.

What is Nosebleed?

Nosebleed (bleeding from nose) is found to be associated with 2,080 drugs and 3,091 conditions by eHealthMe. Check the latest studies of Nosebleed.

On Jul, 12, 2026

3,215 people reported to have side effects when taking Tukysa.
Among them, 64 people (1.99%) have Nosebleed.

Could Tukysa cause Nosebleed?

Among these 64 people:

How long have people been on Tukysa when they have Nosebleed? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Nosebleed when taking Tukysa? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Nosebleed when taking Tukysa? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 5.56 %
  • 50-59: 44.44 %
  • 60+: 50.0 %

What are other drugs people take besides Tukysa? *

  1. Capecitabine: 22 people, 34.38%
  2. Herceptin: 20 people, 31.25%
  3. Xeloda: 8 people, 12.50%
  4. Amlodipine: 5 people, 7.81%
  5. Cymbalta: 5 people, 7.81%
  6. Savaysa: 5 people, 7.81%
  7. Oxycodone: 4 people, 6.25%
  8. Xarelto: 3 people, 4.69%
  9. Atarax: 3 people, 4.69%
  10. Sertraline: 3 people, 4.69%

What are other side effects people have besides Nosebleed? *

  1. Diarrhea: 31 people, 48.44%
  2. Fatigue (feeling of tiredness): 23 people, 35.94%
  3. Nausea (feeling of having an urge to vomit): 20 people, 31.25%
  4. Rashes (redness): 18 people, 28.12%
  5. Stomatitis (inflammation of mucous membrane of mouth): 16 people, 25.00%
  6. Itching: 15 people, 23.44%
  7. Neuropathy Peripheral (surface nerve damage): 14 people, 21.88%
  8. Headache (pain in head): 13 people, 20.31%
  9. Abdominal Pain Upper: 12 people, 18.75%
  10. Pain In Extremity: 11 people, 17.19%

What are the existing conditions these people have? *

  1. Breast Cancer Female: 39 people, 60.94%
  2. Breast Cancer: 12 people, 18.75%
  3. Itching: 3 people, 4.69%
  4. Metastases To Breast (cancer spreads to brain): 2 people, 3.12%
  5. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 1.56%

* Approximation only. Some reports may have incomplete information.

Do you take Tukysa and have Nosebleed?

- Check whether Nosebleed is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tukysa:

Nosebleed treatments and more:

How severe was Nosebleed and when was it recovered:

Expand to all the drugs that have ingredients of tucatinib:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tukysa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nosebleed:

Browse all the conditions that are associated with Nosebleed:

How the study uses the data?

The study uses data from the FDA. It is based on tucatinib (the active ingredients of Tukysa) and Tukysa (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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