Tykerb and Hyperglycemia - a phase IV clinical study of FDA data

Summary:

Hyperglycemia is reported as a side effect among people who take Tykerb (lapatinib ditosylate), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Xeloda, and have Metastases to bone.

The phase IV clinical study analyzes which people have Hyperglycemia when taking Tykerb. It is created by eHealthMe based on reports of 12,186 people who have side effects when taking Tykerb from the FDA, and is updated regularly.

What is Tykerb?

Tykerb has active ingredients of lapatinib ditosylate. It is often used in breast cancer. eHealthMe is studying from 12,231 Tykerb users. Check the latest studies of Tykerb.

What is Hyperglycemia?

Hyperglycemia (high blood sugar) is found to be associated with 1,660 drugs and 2,501 conditions by eHealthMe. Check the latest studies of Hyperglycemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

12,186 people reported to have side effects when taking Tykerb.
Among them, 26 people (0.21%) have Hyperglycemia.

Among these 26 people:

How long have people been on Tykerb when they have Hyperglycemia? *

What is the gender of people who have Hyperglycemia when taking Tykerb? *

female: 88.46 %
male: 11.54 %

What is the age of people who have Hyperglycemia when taking Tykerb? *

What are other drugs people take besides Tykerb? *

What are other side effects people have besides Hyperglycemia? *

Anaemia (lack of blood): 16 people, 61.54%
Diarrhea: 15 people, 57.69%
Neuropathy Peripheral (surface nerve damage): 15 people, 57.69%
Dyspnea (difficult or laboured breathing): 14 people, 53.85%
Fatigue (feeling of tiredness): 14 people, 53.85%
Fever: 14 people, 53.85%
Osteonecrosis Of Jaw (death of bone of jaw): 13 people, 50.00%
Back Pain: 13 people, 50.00%
Osteomyelitis (infection of bone): 12 people, 46.15%
Stress And Anxiety: 12 people, 46.15%

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 8 people, 30.77%
Neoplasm Malignant (cancer tumour): 4 people, 15.38%
Tumor: 2 people, 7.69%
Metastases To Central Nervous System (cancer spreads to central nervous system): 2 people, 7.69%
Sleep Disorder: 1 person, 3.85%
Pain: 1 person, 3.85%
Nausea (feeling of having an urge to vomit): 1 person, 3.85%
Insomnia (sleeplessness): 1 person, 3.85%
Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 1 person, 3.85%
Breast Cancer Recurrent: 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Tykerb and have Hyperglycemia?

- Check whether Hyperglycemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tykerb:

Tykerb (12,231 reports)

Hyperglycemia treatments and more:

Hyperglycemia (48,691 reports)

Browse all side effects of Tykerb:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperglycemia:

Hyperglycemia (1,660 drugs)

Browse all the conditions that are associated with Hyperglycemia:

Hyperglycemia (2,501 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lapatinib ditosylate (the active ingredients of Tykerb) and Tykerb (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.