Tylenol w/ codeine no. 3 and Oedema aggravated - a phase IV clinical study of FDA data

Summary:

Oedema aggravated is reported as a side effect among people who take Tylenol w/ codeine no. 3 (acetaminophen; codeine phosphate), especially for people who are female, 50-59 old, have been taking the drug for 1 - 2 years also take Ativan, and have Depression.

The phase IV clinical study analyzes which people have Oedema aggravated when taking Tylenol w/ codeine no. 3. It is created by eHealthMe based on reports of 4,453 people who have side effects when taking Tylenol w/ codeine no. 3 from the FDA, and is updated regularly.

What is Tylenol w/ codeine no. 3?

Tylenol w/ codeine no. 3 has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 4,920 Tylenol w/ codeine no. 3 users. Check the latest studies of Tylenol w/ codeine no. 3.

What is Oedema aggravated?

Oedema aggravated (fluid collection in tissue) is found to be associated with 1,608 drugs and 584 conditions by eHealthMe. Check the latest studies of Oedema aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

4,453 people reported to have side effects when taking Tylenol w/ codeine no. 3.
Among them, 75 people (1.68%) have Oedema aggravated.

Could Tylenol w/ codeine no. 3 cause Oedema aggravated?

Among these 75 people:

How long have people been on Tylenol w/ codeine no. 3 when they have Oedema aggravated? *

What is the gender of people who have Oedema aggravated when taking Tylenol w/ codeine no. 3? *

female: 64.86 %
male: 35.14 %

What is the age of people who have Oedema aggravated when taking Tylenol w/ codeine no. 3? *

What are other drugs people take besides Tylenol w/ codeine no. 3? *

What are other side effects people have besides Oedema aggravated? *

Fatigue (feeling of tiredness): 35 people, 46.67%
Depression: 32 people, 42.67%
Headache (pain in head): 30 people, 40.00%
Thrombocytopenia (decrease of platelets in blood): 28 people, 37.33%
Stress And Anxiety: 28 people, 37.33%
Nausea (feeling of having an urge to vomit): 27 people, 36.00%
Insomnia (sleeplessness): 26 people, 34.67%
Osteoporosis (bones weak and more likely to break): 25 people, 33.33%
Pain In Jaw: 25 people, 33.33%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 25 people, 33.33%

What are the existing conditions these people have? *

Depression: 20 people, 26.67%
Stress And Anxiety: 19 people, 25.33%
Metastases To Bone (cancer spreads to bone): 17 people, 22.67%
High Blood Cholesterol: 13 people, 17.33%
Nuclear Magnetic Resonance Imaging Brain: 12 people, 16.00%
Device Related Infection: 11 people, 14.67%
Gastritis Erosive (a break in the surface layer of the membrane lining the stomach with infection): 11 people, 14.67%
Herpes Zoster: 11 people, 14.67%
Nausea (feeling of having an urge to vomit): 11 people, 14.67%
Itching: 11 people, 14.67%

* Approximation only. Some reports may have incomplete information.

Do you take Tylenol w/ codeine no. 3 and have Oedema aggravated?

- Check whether Oedema aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tylenol w/ codeine no. 3:

Tylenol w/ codeine no. 3 (4,920 reports)

Oedema aggravated treatments and more:

Oedema aggravated (37 reports)

How severe was Oedema aggravated and when was it recovered:

Oedema aggravated in Tylenol w/ codeine no. 3

Expand to all the drugs that have ingredients of acetaminophen; codeine phosphate:

Oedema aggravated and drugs with ingredients of acetaminophen; codeine phosphate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tylenol w/ codeine no. 3:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Oedema aggravated:

Oedema aggravated (1,608 drugs)

Browse all the conditions that are associated with Oedema aggravated:

Oedema aggravated (584 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; codeine phosphate (the active ingredients of Tylenol w/ codeine no. 3) and Tylenol w/ codeine no. 3 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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