Tylenol w/ codeine no. 3 and Ventricular hypertrophy - a phase IV clinical study of FDA data

Summary:

Ventricular hypertrophy is reported as a side effect among people who take Tylenol w/ codeine no. 3 (acetaminophen; codeine phosphate), especially for people who are female, 60+ old, also take Vioxx, and have Ankylosing spondylitis.

The phase IV clinical study analyzes which people have Ventricular hypertrophy when taking Tylenol w/ codeine no. 3. It is created by eHealthMe based on reports of 4,453 people who have side effects when taking Tylenol w/ codeine no. 3 from the FDA, and is updated regularly.

What is Tylenol w/ codeine no. 3?

Tylenol w/ codeine no. 3 has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 4,920 Tylenol w/ codeine no. 3 users. Check the latest studies of Tylenol w/ codeine no. 3.

What is Ventricular hypertrophy?

Ventricular hypertrophy (enlargement of ventricles (lower chambers) in the heart) is found to be associated with 698 drugs and 794 conditions by eHealthMe. Check the latest studies of Ventricular hypertrophy.



On Jul, 16, 2026

4,453 people reported to have side effects when taking Tylenol w/ codeine no. 3.
Among them, 18 people (0.4%) have Ventricular hypertrophy.

Could Tylenol w/ codeine no. 3 cause Ventricular hypertrophy?

Among these 18 people:

What is the gender of people who have Ventricular hypertrophy when taking Tylenol w/ codeine no. 3? *

  • female: 55.56 %
  • male: 44.44 %

What is the age of people who have Ventricular hypertrophy when taking Tylenol w/ codeine no. 3? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 6.67 %
  • 40-49: 13.33 %
  • 50-59: 0.0 %
  • 60+: 80.0 %

What are other drugs people take besides Tylenol w/ codeine no. 3? *

  1. Vioxx: 13 people, 72.22%
  2. Plavix: 7 people, 38.89%
  3. Xanax: 6 people, 33.33%
  4. Zocor: 6 people, 33.33%
  5. Lanoxin: 6 people, 33.33%
  6. Zestril: 5 people, 27.78%
  7. Lipitor: 5 people, 27.78%
  8. Nexium: 5 people, 27.78%
  9. Aspirin: 5 people, 27.78%
  10. Norvasc: 5 people, 27.78%

What are other side effects people have besides Ventricular hypertrophy? *

  1. Acute Myocardial Infarction (acute heart attack): 8 people, 44.44%
  2. Bundle Branch Block Left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle): 6 people, 33.33%
  3. Loss Of Consciousness: 5 people, 27.78%
  4. Hypotension (abnormally low blood pressure): 5 people, 27.78%
  5. Atrioventricular Block First Degree (heart block first degree): 5 people, 27.78%
  6. Dementia (madness): 5 people, 27.78%
  7. Heart Attack: 5 people, 27.78%
  8. Stress And Anxiety: 5 people, 27.78%
  9. High Blood Pressure: 5 people, 27.78%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 27.78%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 11.11%
  2. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 11.11%
  3. Fatigue (feeling of tiredness): 2 people, 11.11%
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 11.11%
  5. Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Tylenol w/ codeine no. 3 and have Ventricular hypertrophy?

- Check whether Ventricular hypertrophy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tylenol w/ codeine no. 3:

Ventricular hypertrophy treatments and more:

How severe was Ventricular hypertrophy and when was it recovered:

Expand to all the drugs that have ingredients of acetaminophen; codeine phosphate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tylenol w/ codeine no. 3:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ventricular hypertrophy:

Browse all the conditions that are associated with Ventricular hypertrophy:


How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; codeine phosphate (the active ingredients of Tylenol w/ codeine no. 3) and Tylenol w/ codeine no. 3 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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