Tylenol w/ codeine and Contrast media reaction - a phase IV clinical study of FDA data

Summary:

Contrast media reaction is reported as a side effect among people who take Tylenol w/ codeine (acetaminophen; codeine phosphate), especially for people who are male, 60+ old, also take Zocor, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Contrast media reaction when taking Tylenol w/ codeine. It is created by eHealthMe based on reports of 7,307 people who have side effects when taking Tylenol w/ codeine from the FDA, and is updated regularly.

What is Tylenol w/ codeine?

Tylenol w/ codeine has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 8,107 Tylenol w/ codeine users. Check the latest studies of Tylenol w/ codeine.

What is Contrast media reaction?

Contrast media reaction (reaction associated with the use of intravenous contrast material during radiology) is found to be associated with 226 drugs and 334 conditions by eHealthMe. Check the latest studies of Contrast media reaction.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

7,307 people reported to have side effects when taking Tylenol w/ codeine.
Among them, 11 people (0.15%) have Contrast media reaction.

Could Tylenol w/ codeine cause Contrast media reaction?

Among these 11 people:

What is the gender of people who have Contrast media reaction when taking Tylenol w/ codeine? *

female: 0.0 %
male: 100 %

What is the age of people who have Contrast media reaction when taking Tylenol w/ codeine? *

What are other drugs people take besides Tylenol w/ codeine? *

What are other side effects people have besides Contrast media reaction? *

Intervertebral Disc Protrusion (spinal disc protrusion): 11 people, 100.00%
Joint Pain: 11 people, 100.00%
Bone Disorder: 11 people, 100.00%
Oral Disorder (mouth disease): 11 people, 100.00%
Neuritis (inflammation of nerve): 11 people, 100.00%
Neck Pain: 11 people, 100.00%
Muscle Spasms (muscle contraction): 11 people, 100.00%
Bone Lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 11 people, 100.00%
Bruxism (habitual grinding of the teeth, typically during sleep): 11 people, 100.00%
Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 11 people, 100.00%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 11 people, 100.00%
High Blood Pressure: 11 people, 100.00%
High Blood Cholesterol: 11 people, 100.00%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 11 people, 100.00%
Tic (a sudden, repetitive, nonrhythmic motor movement or vocalization involving discrete muscle groups): 3 people, 27.27%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Tylenol w/ codeine and have Contrast media reaction?

- Check whether Contrast media reaction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tylenol w/ codeine:

Tylenol w/ codeine (8,107 reports)

Contrast media reaction treatments and more:

Contrast media reaction (2,833 reports)

How severe was Contrast media reaction and when was it recovered:

Contrast media reaction in Tylenol w/ codeine

Expand to all the drugs that have ingredients of acetaminophen; codeine phosphate:

Contrast media reaction and drugs with ingredients of acetaminophen; codeine phosphate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tylenol w/ codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Contrast media reaction:

Contrast media reaction (226 drugs)

Browse all the conditions that are associated with Contrast media reaction:

Contrast media reaction (334 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; codeine phosphate (the active ingredients of Tylenol w/ codeine) and Tylenol w/ codeine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.