Tylenol w/ codeine and Meningitis - a phase IV clinical study of FDA data

Summary:

Meningitis is reported as a side effect among people who take Tylenol w/ codeine (acetaminophen; codeine phosphate), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Lorazepam, and have Drug dependence.

The phase IV clinical study analyzes which people have Meningitis when taking Tylenol w/ codeine. It is created by eHealthMe based on reports of 7,307 people who have side effects when taking Tylenol w/ codeine from the FDA, and is updated regularly.

What is Tylenol w/ codeine?

Tylenol w/ codeine has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 8,107 Tylenol w/ codeine users. Check the latest studies of Tylenol w/ codeine.

What is Meningitis?

Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges) is found to be associated with 651 drugs and 882 conditions by eHealthMe. Check the latest studies of Meningitis.



On Jul, 24, 2026

7,307 people reported to have side effects when taking Tylenol w/ codeine.
Among them, 13 people (0.18%) have Meningitis.

Could Tylenol w/ codeine cause Meningitis?

Among these 13 people:

How long have people been on Tylenol w/ codeine when they have Meningitis? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Meningitis when taking Tylenol w/ codeine? *

  • female: 71.43 %
  • male: 28.57 %

What is the age of people who have Meningitis when taking Tylenol w/ codeine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 85.71 %
  • 50-59: 0.0 %
  • 60+: 14.29 %

What are other drugs people take besides Tylenol w/ codeine? *

  1. Lorazepam: 8 people, 61.54%
  2. Zofran: 7 people, 53.85%
  3. Zometa: 6 people, 46.15%
  4. Avelox: 6 people, 46.15%
  5. Navelbine: 6 people, 46.15%
  6. Naloxone: 6 people, 46.15%
  7. Methotrexate: 6 people, 46.15%
  8. Lasix: 6 people, 46.15%
  9. Avastin: 6 people, 46.15%
  10. Herceptin: 6 people, 46.15%

What are other side effects people have besides Meningitis? *

  1. Nausea (feeling of having an urge to vomit): 9 people, 69.23%
  2. Swallowing Difficulty: 8 people, 61.54%
  3. Fever: 7 people, 53.85%
  4. Weight Decreased: 7 people, 53.85%
  5. Thrombocytopenia (decrease of platelets in blood): 7 people, 53.85%
  6. Anaemia (lack of blood): 7 people, 53.85%
  7. Metastases To Meninges (cancer spreads to meninges): 6 people, 46.15%
  8. Metastases To Central Nervous System (cancer spreads to central nervous system): 6 people, 46.15%
  9. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 6 people, 46.15%
  10. Pain In Jaw: 6 people, 46.15%

What are the existing conditions these people have? *

  1. Drug Dependence: 6 people, 46.15%
  2. Viral Sinusitis (inflammation of the sinuses with a viral infection): 1 person, 7.69%
  3. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Tylenol w/ codeine and have Meningitis?

- Check whether Meningitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tylenol w/ codeine:

Meningitis treatments and more:

How severe was Meningitis and when was it recovered:

Expand to all the drugs that have ingredients of acetaminophen; codeine phosphate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tylenol w/ codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Meningitis:

Browse all the conditions that are associated with Meningitis:


How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; codeine phosphate (the active ingredients of Tylenol w/ codeine) and Tylenol w/ codeine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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