Tylenol and Calculus bladder - a phase IV clinical study of FDA data

Summary:

Calculus bladder is reported as a side effect among people who take Tylenol (acetaminophen), especially for people who are male, 50-59 old, also take Vitamin D3, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Calculus bladder when taking Tylenol. It is created by eHealthMe based on reports of 217,809 people who have side effects when taking Tylenol from the FDA, and is updated regularly.

What is Tylenol?

Tylenol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 222,306 Tylenol users. Check the latest studies of Tylenol.

What is Calculus bladder?

Calculus bladder (bladder stone) is found to be associated with 230 drugs and 614 conditions by eHealthMe. Check the latest studies of Calculus bladder.

On Mar, 26, 2026

217,809 people reported to have side effects when taking Tylenol.
Among them, 29 people (0.01%) have Calculus bladder.

Among these 29 people:

What is the gender of people who have Calculus bladder when taking Tylenol? *

female: 44.44 %
male: 55.56 %

What is the age of people who have Calculus bladder when taking Tylenol? *

What are other drugs people take besides Tylenol? *

Rebif: 6 people, 20.69%
Vitamin D3: 6 people, 20.69%
Tysabri: 5 people, 17.24%
Ampyra: 4 people, 13.79%
Miralax: 4 people, 13.79%
Neurontin: 4 people, 13.79%
Vitamin C: 4 people, 13.79%
Colace: 4 people, 13.79%
Zofran: 3 people, 10.34%
Hydroxychloroquine Sulfate: 3 people, 10.34%

What are other side effects people have besides Calculus bladder? *

Urinary Tract Infection: 14 people, 48.28%
Kidney Stones: 9 people, 31.03%
Weakness: 7 people, 24.14%
Fatigue (feeling of tiredness): 6 people, 20.69%
Dizziness: 5 people, 17.24%
Neurogenic Bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 5 people, 17.24%
Pneumonia: 5 people, 17.24%
Sepsis (a severe blood infection that can lead to organ failure and death): 5 people, 17.24%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 17.24%
Weight Decreased: 4 people, 13.79%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 12 people, 41.38%
Multiple Myeloma (cancer of the plasma cells): 3 people, 10.34%
High Blood Pressure: 3 people, 10.34%
Neurogenic Bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 2 people, 6.90%
Constipation: 2 people, 6.90%
Mobility Decreased (ability to move is reduced): 2 people, 6.90%
Muscle Spasms (muscle contraction): 2 people, 6.90%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 6.90%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 2 people, 6.90%
Bladder Cancer: 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

Do you take Tylenol and have Calculus bladder?

- Check whether Calculus bladder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tylenol:

Tylenol (222,306 reports)

Browse all side effects of Tylenol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Calculus bladder:

Calculus bladder (230 drugs)

Browse all the conditions that are associated with Calculus bladder:

Calculus bladder (614 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen (the active ingredients of Tylenol) and Tylenol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.