Tylenol and Mitral valve hypoplasia - a phase IV clinical study of FDA data

Summary:

Mitral valve hypoplasia is reported as a side effect among people who take Tylenol (acetaminophen), especially for people who are female, 0-1 old, also take Paxil, and have Depression.

The phase IV clinical study analyzes which people have Mitral valve hypoplasia when taking Tylenol. It is created by eHealthMe based on reports of 217,809 people who have side effects when taking Tylenol from the FDA, and is updated regularly.

What is Tylenol?

Tylenol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 222,310 Tylenol users. Check the latest studies of Tylenol.

What is Mitral valve hypoplasia?

Mitral valve hypoplasia (mitral valves are either too small to allow sufficient blood) is found to be associated with 24 drugs and 44 conditions by eHealthMe. Check the latest studies of Mitral valve hypoplasia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

217,809 people reported to have side effects when taking Tylenol.
Among them, 16 people (0.01%) have Mitral valve hypoplasia.

Could Tylenol cause Mitral valve hypoplasia?

Among these 16 people:

What is the gender of people who have Mitral valve hypoplasia when taking Tylenol? *

female: 75 %
male: 25 %

What is the age of people who have Mitral valve hypoplasia when taking Tylenol? *

What are other drugs people take besides Tylenol? *

What are other side effects people have besides Mitral valve hypoplasia? *

Right Ventricular Hypertrophy (right ventricular enlargement): 10 people, 62.50%
Ventricular Dysfunction (heart dysfunction): 8 people, 50.00%
Arrhythmias (irregular heartbeat): 8 people, 50.00%
Drug Exposure During Pregnancy: 7 people, 43.75%
Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 6 people, 37.50%
Hepatic Congestion (liver congestion): 5 people, 31.25%
Respiratory Distress Syndrome (Rds) In Infants (respiratory disease of newborn babies, especially premature babies, characterized by distressful breathing, cyanosis, and the formation of a glassy membrane over the alveoli of the lungs): 5 people, 31.25%
Lung Disorder (lung disease): 5 people, 31.25%
Sepsis (a severe blood infection that can lead to organ failure and death): 5 people, 31.25%
Aortic Stenosis (obstruction to the outflow of blood from the left ventricle into the aorta): 5 people, 31.25%

What are the existing conditions these people have? *

Depression: 12 people, 75.00%
Stress And Anxiety: 11 people, 68.75%
Upper Respiratory Tract Infection: 4 people, 25.00%
Teething (process by which an infant's first teeth grows): 4 people, 25.00%
Abdominal Pain: 4 people, 25.00%
The Flu (the flu is caused by an influenza virus): 1 person, 6.25%
Oedema (fluid collection in tissue): 1 person, 6.25%
Mood Swings (an extreme or rapid change in mood): 1 person, 6.25%
Liver Disorder (liver diseases): 1 person, 6.25%
Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Tylenol and have Mitral valve hypoplasia?

- Check whether Mitral valve hypoplasia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tylenol:

Tylenol (222,310 reports)

Browse all side effects of Tylenol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mitral valve hypoplasia:

Mitral valve hypoplasia (24 drugs)

Browse all the conditions that are associated with Mitral valve hypoplasia:

Mitral valve hypoplasia (44 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen (the active ingredients of Tylenol) and Tylenol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.