Tysabri and Hypocalcaemia - a phase IV clinical study of FDA data
Summary:
Hypocalcaemia is reported as a side effect among people who take Tysabri (natalizumab), especially for people who are female, 40-49 old, have been taking the drug for 5 - 10 years also take Calcium, and have High blood pressure.
The phase IV clinical study analyzes which people have Hypocalcaemia when taking Tysabri. It is created by eHealthMe based on reports of 220,870 people who have side effects when taking Tysabri from the FDA, and is updated regularly.
What is Tysabri?
Tysabri has active ingredients of natalizumab. It is often used in multiple sclerosis. eHealthMe is studying from 221,369 Tysabri users. Check the latest studies of Tysabri.
What is Hypocalcaemia?
Hypocalcaemia (levels of calcium in blood serum are abnormally low) is found to be associated with 1,207 drugs and 1,302 conditions by eHealthMe. Check the latest studies of Hypocalcaemia.
220,870 people reported to have side effects when taking Tysabri.
Among them, 23 people (0.01%) have Hypocalcaemia.

Among these 23 people:
How long have people been on Tysabri when they have Hypocalcaemia? *
- < 1 month: 0.0 %
- 1 - 6 months: 10 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 10 %
- 2 - 5 years: 30 %
- 5 - 10 years: 50 %
- 10+ years: 0.0 %
What is the gender of people who have Hypocalcaemia when taking Tysabri? *
- female: 86.96 %
- male: 13.04 %
What is the age of people who have Hypocalcaemia when taking Tysabri? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 4.55 %
- 20-29: 0.0 %
- 30-39: 13.64 %
- 40-49: 50.0 %
- 50-59: 22.73 %
- 60+: 9.09 %
What are other drugs people take besides Tysabri? *
- Calcium: 7 people, 30.43%
- Amlodipine: 6 people, 26.09%
- Xarelto: 6 people, 26.09%
- Novalgin: 5 people, 21.74%
- Nexium: 5 people, 21.74%
- Vitamin D: 4 people, 17.39%
- Risperdal: 3 people, 13.04%
- Imitrex: 2 people, 8.70%
- Macrobid: 2 people, 8.70%
- Drisdol: 2 people, 8.70%
What are other side effects people have besides Hypocalcaemia? *
- Hypokalemia (low potassium): 12 people, 52.17%
- Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 7 people, 30.43%
- Supraventricular Extrasystoles (premature electrical impulse in the heart, generated above the level of the ventricle): 6 people, 26.09%
- Drug Hypersensitivity: 6 people, 26.09%
- Pleurisy (inflammation of the pleurae, which causes pain when breathing): 6 people, 26.09%
- Pulmonary Hypertension (increase in blood pressure in the lung artery): 6 people, 26.09%
- Pulmonary Embolism (blockage of the main artery of the lung): 6 people, 26.09%
- Cor Pulmonale Acute (rapid enlargement of the right ventricle of the heart): 6 people, 26.09%
- Dyspnea (difficult or laboured breathing): 5 people, 21.74%
- General Physical Health Deterioration (weak health status): 5 people, 21.74%
What are the existing conditions these people have? *
- Pain In Extremity: 6 people, 26.09%
- High Blood Pressure: 6 people, 26.09%
- Pleurisy (inflammation of the pleurae, which causes pain when breathing): 5 people, 21.74%
- Sleep Disorder: 2 people, 8.70%
- Muscle Spasms (muscle contraction): 2 people, 8.70%
- Migraine (headache): 2 people, 8.70%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 4.35%
- Pain: 1 person, 4.35%
- Osteoporosis (bones weak and more likely to break): 1 person, 4.35%
- Menopausal Symptoms: 1 person, 4.35%
* Approximation only. Some reports may have incomplete information.
Do you take Tysabri and have Hypocalcaemia?
- Check whether Hypocalcaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Tysabri:
- Tysabri (221,369 reports)
Hypocalcaemia treatments and more:
- Hypocalcaemia (26,346 reports)
How severe was Hypocalcaemia and when was it recovered:
Expand to all the drugs that have ingredients of natalizumab:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Tysabri:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Hypocalcaemia:
- Hypocalcaemia (1,207 drugs)
Browse all the conditions that are associated with Hypocalcaemia:
- Hypocalcaemia (1,302 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on natalizumab (the active ingredients of Tysabri) and Tysabri (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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