Tysabri and Nocturia aggravated - a phase IV clinical study of FDA data

Summary:

Nocturia aggravated is reported as a side effect among people who take Tysabri (natalizumab), especially for people who are female, 50-59 old, have been taking the drug for 2 - 5 years also take Avonex, and have Gait disturbance.

The phase IV clinical study analyzes which people have Nocturia aggravated when taking Tysabri. It is created by eHealthMe based on reports of 220,870 people who have side effects when taking Tysabri from the FDA, and is updated regularly.

What is Tysabri?

Tysabri has active ingredients of natalizumab. It is often used in multiple sclerosis. eHealthMe is studying from 221,369 Tysabri users. Check the latest studies of Tysabri.

What is Nocturia aggravated?

Nocturia aggravated (a need to get up in the night to urinate) is found to be associated with 953 drugs and 331 conditions by eHealthMe. Check the latest studies of Nocturia aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

220,870 people reported to have side effects when taking Tysabri.
Among them, 53 people (0.02%) have Nocturia aggravated.

Could Tysabri cause Nocturia aggravated?

Among these 53 people:

How long have people been on Tysabri when they have Nocturia aggravated? *

What is the gender of people who have Nocturia aggravated when taking Tysabri? *

female: 83.02 %
male: 16.98 %

What is the age of people who have Nocturia aggravated when taking Tysabri? *

What are other drugs people take besides Tysabri? *

What are other side effects people have besides Nocturia aggravated? *

Fatigue (feeling of tiredness): 30 people, 56.60%
Weakness: 24 people, 45.28%
Urinary Tract Infection: 19 people, 35.85%
Hypoaesthesia (reduced sense of touch or sensation): 17 people, 32.08%
Joint Pain: 16 people, 30.19%
Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 16 people, 30.19%
Depression: 15 people, 28.30%
Gait Disturbance: 14 people, 26.42%
Balance Disorder: 14 people, 26.42%
Back Pain: 14 people, 26.42%

What are the existing conditions these people have? *

Pain: 8 people, 15.09%
Gait Disturbance: 8 people, 15.09%
Cough: 7 people, 13.21%
Urethritis Noninfective (inflammation of the urethra - non infective): 7 people, 13.21%
Bladder Disorder: 7 people, 13.21%
Blood Glucose Abnormal: 7 people, 13.21%
Depression: 3 people, 5.66%
Diarrhea: 3 people, 5.66%
Osteoporosis (bones weak and more likely to break): 3 people, 5.66%
Multiple Myeloma (cancer of the plasma cells): 3 people, 5.66%

* Approximation only. Some reports may have incomplete information.

Do you take Tysabri and have Nocturia aggravated?

- Check whether Nocturia aggravated is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tysabri:

Tysabri (221,369 reports)

Browse all side effects of Tysabri:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nocturia aggravated:

Nocturia aggravated (953 drugs)

Browse all the conditions that are associated with Nocturia aggravated:

Nocturia aggravated (331 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on natalizumab (the active ingredients of Tysabri) and Tysabri (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.