Tyvaso and Diastolic dysfunction - a phase IV clinical study of FDA data

Summary:

Diastolic dysfunction is reported as a side effect among people who take Tyvaso (treprostinil sodium), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Lasix, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Diastolic dysfunction when taking Tyvaso. It is created by eHealthMe based on reports of 37,923 people who have side effects when taking Tyvaso from the FDA, and is updated regularly.

What is Tyvaso?

Tyvaso has active ingredients of treprostinil sodium. eHealthMe is studying from 37,941 Tyvaso users. Check the latest studies of Tyvaso.

What is Diastolic dysfunction?

Diastolic dysfunction is found to be associated with 685 drugs and 630 conditions by eHealthMe. Check the latest studies of Diastolic dysfunction.

On Jul, 03, 2026

37,923 people reported to have side effects when taking Tyvaso.
Among them, 13 people (0.03%) have Diastolic dysfunction.

Could Tyvaso cause Diastolic dysfunction?

Among these 13 people:

How long have people been on Tyvaso when they have Diastolic dysfunction? *

What is the gender of people who have Diastolic dysfunction when taking Tyvaso? *

female: 92.31 %
male: 7.69 %

What is the age of people who have Diastolic dysfunction when taking Tyvaso? *

What are other drugs people take besides Tyvaso? *

What are other side effects people have besides Diastolic dysfunction? *

Dyspnea (difficult or laboured breathing): 8 people, 61.54%
Oedema Peripheral (superficial swelling): 6 people, 46.15%
Cardiac Failure Congestive: 6 people, 46.15%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 46.15%
Rales (an abnormal respiratory sound characterized by fine crackles): 4 people, 30.77%
Fatigue (feeling of tiredness): 4 people, 30.77%
Pain In Extremity: 4 people, 30.77%
Wheezing (a high-pitched whistling sound made while you breath): 4 people, 30.77%
Acute Respiratory Failure: 4 people, 30.77%
Headache (pain in head): 3 people, 23.08%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 9 people, 69.23%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 4 people, 30.77%
Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 2 people, 15.38%
Chest Pain: 2 people, 15.38%
Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 1 person, 7.69%
Sleep Disorder: 1 person, 7.69%
Pulmonary Embolism (blockage of the main artery of the lung): 1 person, 7.69%
Oedema (fluid collection in tissue): 1 person, 7.69%
Mixed Connective Tissue Disease (an autoimmune disease, in which the body's defence system attacks itself): 1 person, 7.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Tyvaso and have Diastolic dysfunction?

- Check whether Diastolic dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tyvaso:

Tyvaso (37,941 reports)

Browse all side effects of Tyvaso:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diastolic dysfunction:

Diastolic dysfunction (685 drugs)

Browse all the conditions that are associated with Diastolic dysfunction:

Diastolic dysfunction (630 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on treprostinil sodium (the active ingredients of Tyvaso) and Tyvaso (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.