Tyvaso and Mitral valve incompetence - a phase IV clinical study of FDA data

Summary:

Mitral valve incompetence is reported as a side effect among people who take Tyvaso (treprostinil sodium), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Tadalafil, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Mitral valve incompetence when taking Tyvaso. It is created by eHealthMe based on reports of 37,923 people who have side effects when taking Tyvaso from the FDA, and is updated regularly.

What is Tyvaso?

Tyvaso has active ingredients of treprostinil sodium. eHealthMe is studying from 37,941 Tyvaso users. Check the latest studies of Tyvaso.

What is Mitral valve incompetence?

Mitral valve incompetence (inefficient heart valve) is found to be associated with 1,435 drugs and 1,279 conditions by eHealthMe. Check the latest studies of Mitral valve incompetence.

On Aug, 11, 2026

37,923 people reported to have side effects when taking Tyvaso.
Among them, 13 people (0.03%) have Mitral valve incompetence.

Could Tyvaso cause Mitral valve incompetence?

Among these 13 people:

How long have people been on Tyvaso when they have Mitral valve incompetence? *

What is the gender of people who have Mitral valve incompetence when taking Tyvaso? *

female: 84.62 %
male: 15.38 %

What is the age of people who have Mitral valve incompetence when taking Tyvaso? *

What are other drugs people take besides Tyvaso? *

What are other side effects people have besides Mitral valve incompetence? *

Tricuspid Valve Incompetence (inefficient heart valve): 6 people, 46.15%
Dizziness: 4 people, 30.77%
Head Injury: 3 people, 23.08%
Cough: 3 people, 23.08%
Disease Progression: 3 people, 23.08%
Confusional State: 2 people, 15.38%
Pulmonary Valve Incompetence: 2 people, 15.38%
Pulmonary Oedema (fluid accumulation in the lungs): 2 people, 15.38%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 15.38%
Diarrhea: 2 people, 15.38%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 11 people, 84.62%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 15.38%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.69%
Oedema Peripheral (superficial swelling): 1 person, 7.69%
Interstitial Lung Disease: 1 person, 7.69%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 1 person, 7.69%
High Blood Pressure: 1 person, 7.69%
Diabetes: 1 person, 7.69%
Arrhythmias (irregular heartbeat): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Tyvaso and have Mitral valve incompetence?

- Check whether Mitral valve incompetence is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tyvaso:

Tyvaso (37,941 reports)

Browse all side effects of Tyvaso:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mitral valve incompetence:

Mitral valve incompetence (1,435 drugs)

Browse all the conditions that are associated with Mitral valve incompetence:

Mitral valve incompetence (1,279 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on treprostinil sodium (the active ingredients of Tyvaso) and Tyvaso (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.