Ultomiris and Herpes zoster - a phase IV clinical study of FDA data

Summary:

Herpes zoster is reported as a side effect among people who take Ultomiris (ravulizumab-cwvz), especially for people who are female, 60+ old, also take Losartan, and have Myasthenia gravis.

The phase IV clinical study analyzes which people have Herpes zoster when taking Ultomiris. It is created by eHealthMe based on reports of 5,773 people who have side effects when taking Ultomiris from the FDA, and is updated regularly.

What is Ultomiris?

Ultomiris has active ingredients of ravulizumab-cwvz. eHealthMe is studying from 5,775 Ultomiris users. Check the latest studies of Ultomiris.

What is Herpes zoster?

Herpes zoster is found to be associated with 1,820 drugs and 2,172 conditions by eHealthMe. Check the latest studies of Herpes zoster.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Jul, 28, 2026

5,773 people reported to have side effects when taking Ultomiris.
Among them, 16 people (0.28%) have Herpes zoster.

Could Ultomiris cause Herpes zoster?

Among these 16 people:

What is the gender of people who have Herpes zoster when taking Ultomiris? *

  • female: 64.29 %
  • male: 35.71 %

What is the age of people who have Herpes zoster when taking Ultomiris? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 14.29 %
  • 40-49: 0.0 %
  • 50-59: 14.29 %
  • 60+: 71.43 %

What are other drugs people take besides Ultomiris? *

  1. Vitamin D3: 1 person, 6.25%
  2. Vitamin B12: 1 person, 6.25%
  3. Spironolactone: 1 person, 6.25%
  4. Protonix: 1 person, 6.25%
  5. Primidone: 1 person, 6.25%
  6. Prednisone: 1 person, 6.25%
  7. Mestinon: 1 person, 6.25%
  8. Losartan: 1 person, 6.25%

What are other side effects people have besides Herpes zoster? *

  1. Memory Loss: 4 people, 25.00%
  2. Pain: 3 people, 18.75%
  3. Fatigue (feeling of tiredness): 3 people, 18.75%
  4. Confusional State: 2 people, 12.50%
  5. Headache (pain in head): 2 people, 12.50%
  6. Rashes (redness): 2 people, 12.50%
  7. Pseudomonal Sepsis (pseudomonas infections are diseases caused by a bacterium from the genus pseudomonas): 2 people, 12.50%
  8. Pain In Extremity: 2 people, 12.50%
  9. Dizziness: 1 person, 6.25%
  10. Groin Pain: 1 person, 6.25%

What are the existing conditions these people have? *

  1. Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 7 people, 43.75%
  2. Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 5 people, 31.25%

* Approximation only. Some reports may have incomplete information.

Do you take Ultomiris and have Herpes zoster?

- Check whether Herpes zoster is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ultomiris:

Herpes zoster treatments and more:

How severe was Herpes zoster and when was it recovered:

Expand to all the drugs that have ingredients of ravulizumab-cwvz:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ultomiris:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Herpes zoster:

Browse all the conditions that are associated with Herpes zoster:


How the study uses the data?

The study uses data from the FDA. It is based on ravulizumab-cwvz (the active ingredients of Ultomiris) and Ultomiris (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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