Ultracet and Compression fracture - a phase IV clinical study of FDA data

Summary:

Compression fracture is reported as a side effect among people who take Ultracet (acetaminophen; tramadol hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Zometa, and have Metastases to bone.

The phase IV clinical study analyzes which people have Compression fracture when taking Ultracet. It is created by eHealthMe based on reports of 6,139 people who have side effects when taking Ultracet from the FDA, and is updated regularly.

What is Ultracet?

Ultracet has active ingredients of acetaminophen; tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 6,351 Ultracet users. Check the latest studies of Ultracet.

What is Compression fracture?

Compression fracture (fracture due to pressure caused by injury) is found to be associated with 794 drugs and 636 conditions by eHealthMe. Check the latest studies of Compression fracture.

On Jul, 16, 2026

6,139 people reported to have side effects when taking Ultracet.
Among them, 83 people (1.35%) have Compression fracture.

$Could Ultracet cause Compression fracture?$

Among these 83 people:

How long have people been on Ultracet when they have Compression fracture? *

What is the gender of people who have Compression fracture when taking Ultracet? *

female: 57.83 %
male: 42.17 %

What is the age of people who have Compression fracture when taking Ultracet? *

What are other drugs people take besides Ultracet? *

What are other side effects people have besides Compression fracture? *

Anaemia (lack of blood): 72 people, 86.75%
Osteonecrosis Of Jaw (death of bone of jaw): 68 people, 81.93%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 64 people, 77.11%
Osteopenia (a condition where bone mineral density is lower than normal): 57 people, 68.67%
Pneumonia: 55 people, 66.27%
Chest Pain: 54 people, 65.06%
Enlarged Heart: 50 people, 60.24%
Fatigue (feeling of tiredness): 50 people, 60.24%
Tenderness (pain or discomfort when an affected area is touched): 49 people, 59.04%
Intervertebral Disc Degeneration (spinal disc degeneration): 47 people, 56.63%

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 17 people, 20.48%
High Blood Pressure: 16 people, 19.28%
Depression: 15 people, 18.07%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 15 people, 18.07%
Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 11 people, 13.25%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 10 people, 12.05%
Multiple Myeloma (cancer of the plasma cells): 6 people, 7.23%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 4.82%
Fever: 2 people, 2.41%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 2.41%

* Approximation only. Some reports may have incomplete information.

Do you take Ultracet and have Compression fracture?

- Check whether Compression fracture is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ultracet:

Ultracet (6,351 reports)

Compression fracture treatments and more:

Compression fracture (7,185 reports)

How severe was Compression fracture and when was it recovered:

Compression fracture in Ultracet

Expand to all the drugs that have ingredients of acetaminophen; tramadol hydrochloride:

Compression fracture and drugs with ingredients of acetaminophen; tramadol hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ultracet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Compression fracture:

Compression fracture (794 drugs)

Browse all the conditions that are associated with Compression fracture:

Compression fracture (636 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; tramadol hydrochloride (the active ingredients of Ultracet) and Ultracet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.