Ultracet and Sedation aggravated - a phase IV clinical study of FDA data

Summary:

Sedation aggravated is reported as a side effect among people who take Ultracet (acetaminophen; tramadol hydrochloride), especially for people who are female, 50-59 old, also take Lyrica, and have Cervical cord compression.

The phase IV clinical study analyzes which people have Sedation aggravated when taking Ultracet. It is created by eHealthMe based on reports of 6,139 people who have side effects when taking Ultracet from the FDA, and is updated regularly.

What is Ultracet?

Ultracet has active ingredients of acetaminophen; tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 6,351 Ultracet users. Check the latest studies of Ultracet.

What is Sedation aggravated?

Sedation aggravated is found to be associated with 1,153 drugs and 493 conditions by eHealthMe. Check the latest studies of Sedation aggravated.

On Jul, 14, 2026

6,139 people reported to have side effects when taking Ultracet.
Among them, 17 people (0.28%) have Sedation aggravated.

Could Ultracet cause Sedation aggravated?

Among these 17 people:

What is the gender of people who have Sedation aggravated when taking Ultracet? *

female: 58.82 %
male: 41.18 %

What is the age of people who have Sedation aggravated when taking Ultracet? *

What are other drugs people take besides Ultracet? *

What are other side effects people have besides Sedation aggravated? *

Dizziness: 6 people, 35.29%
Headache (pain in head): 6 people, 35.29%
Nausea (feeling of having an urge to vomit): 6 people, 35.29%
Nausea And Vomiting: 5 people, 29.41%
Head Discomfort: 4 people, 23.53%
Hypoaesthesia (reduced sense of touch or sensation): 4 people, 23.53%
Constipation: 4 people, 23.53%
Drowsiness: 4 people, 23.53%
Gait Disturbance: 3 people, 17.65%
Hypoaesthesia Oral (reduced sense of touch or sensation in mouth): 3 people, 17.65%

What are the existing conditions these people have? *

Cervical Cord Compression (compression of spinal cord at site of cervical vertebrae): 3 people, 17.65%
Stress And Anxiety: 1 person, 5.88%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 1 person, 5.88%
Pain In Extremity: 1 person, 5.88%
Neuralgia (pain in one or more nerves): 1 person, 5.88%
Joint Injury: 1 person, 5.88%
Ill-Defined Disorder: 1 person, 5.88%
Dysmenorrhea (painful menstruation): 1 person, 5.88%
Depression: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Ultracet and have Sedation aggravated?

- Check whether Sedation aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ultracet:

Ultracet (6,351 reports)

Sedation aggravated treatments and more:

Sedation aggravated (20 reports)

How severe was Sedation aggravated and when was it recovered:

Sedation aggravated in Ultracet

Expand to all the drugs that have ingredients of acetaminophen; tramadol hydrochloride:

Sedation aggravated and drugs with ingredients of acetaminophen; tramadol hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ultracet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sedation aggravated:

Sedation aggravated (1,153 drugs)

Browse all the conditions that are associated with Sedation aggravated:

Sedation aggravated (493 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; tramadol hydrochloride (the active ingredients of Ultracet) and Ultracet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.