Ultracet and Thyroid cancer - a phase IV clinical study of FDA data

Summary:

Thyroid cancer is reported as a side effect among people who take Ultracet (acetaminophen; tramadol hydrochloride), especially for people who are female, 40-49 old, have been taking the drug for 10+ years also take Celecoxib, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Thyroid cancer when taking Ultracet. It is created by eHealthMe based on reports of 6,139 people who have side effects when taking Ultracet from the FDA, and is updated regularly.

What is Ultracet?

Ultracet has active ingredients of acetaminophen; tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 6,351 Ultracet users. Check the latest studies of Ultracet.

What is Thyroid cancer?

Thyroid cancer is found to be associated with 596 drugs and 840 conditions by eHealthMe. Check the latest studies of Thyroid cancer.

On Jul, 14, 2026

6,139 people reported to have side effects when taking Ultracet.
Among them, 12 people (0.2%) have Thyroid cancer.

Among these 12 people:

How long have people been on Ultracet when they have Thyroid cancer? *

What is the gender of people who have Thyroid cancer when taking Ultracet? *

female: 91.67 %
male: 8.33 %

What is the age of people who have Thyroid cancer when taking Ultracet? *

What are other drugs people take besides Ultracet? *

Prednisolone: 6 people, 50.00%
Pyridoxine Hydrochloride: 6 people, 50.00%
Methotrexate: 6 people, 50.00%
Omeprazole: 6 people, 50.00%
Celecoxib: 6 people, 50.00%
Folic Acid: 5 people, 41.67%
Synthroid: 5 people, 41.67%
Medrol: 4 people, 33.33%
Dilaudid: 4 people, 33.33%
Neurontin: 4 people, 33.33%

What are other side effects people have besides Thyroid cancer? *

Lung Neoplasm (tumour of lung): 9 people, 75.00%
Pancreatic Carcinoma (pancreatic cancer): 4 people, 33.33%
Lacunar Infarction (a type of stroke): 3 people, 25.00%
Hepatomegaly (abnormal enlargement of the liver): 3 people, 25.00%
Electrocardiogram Qrs Complex Abnormal: 3 people, 25.00%
Electrocardiogram Qt Prolonged: 3 people, 25.00%
Enlarged Heart: 3 people, 25.00%
Fatigue (feeling of tiredness): 3 people, 25.00%
Fistula (an abnormal connection or passageway between two): 3 people, 25.00%
Gingival Bleeding (bleeding gums): 3 people, 25.00%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 58.33%
Osteoporosis (bones weak and more likely to break): 3 people, 25.00%
Bone Loss: 3 people, 25.00%
Thyroid Diseases: 1 person, 8.33%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 8.33%
Cerebral Infarction (less blood supply to brain resulting tissue damage): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Ultracet and have Thyroid cancer?

- Check whether Thyroid cancer is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ultracet:

Ultracet (6,351 reports)

Thyroid cancer treatments and more:

Thyroid cancer (24,393 reports)

How severe was Thyroid cancer and when was it recovered:

Thyroid cancer in Ultracet

Expand to all the drugs that have ingredients of acetaminophen; tramadol hydrochloride:

Thyroid cancer and drugs with ingredients of acetaminophen; tramadol hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ultracet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thyroid cancer:

Thyroid cancer (596 drugs)

Browse all the conditions that are associated with Thyroid cancer:

Thyroid cancer (840 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; tramadol hydrochloride (the active ingredients of Ultracet) and Ultracet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.