Uniphyl and Chills - a phase IV clinical study of FDA data

Summary:

Chills is reported as a side effect among people who take Uniphyl (theophylline), especially for people who are female, 50-59 old, also take Singulair, and have Asthma.

The phase IV clinical study analyzes which people have Chills when taking Uniphyl. It is created by eHealthMe based on reports of 3,071 people who have side effects when taking Uniphyl from the FDA, and is updated regularly.

What is Uniphyl?

Uniphyl has active ingredients of theophylline. eHealthMe is studying from 3,086 Uniphyl users. Check the latest studies of Uniphyl.

What is Chills?

Chills (felling of cold) is found to be associated with 2,554 drugs and 3,475 conditions by eHealthMe. Check the latest studies of Chills.

On Aug, 02, 2026

3,071 people reported to have side effects when taking Uniphyl.
Among them, 34 people (1.11%) have Chills.

Among these 34 people:

What is the gender of people who have Chills when taking Uniphyl? *

female: 78.12 %
male: 21.88 %

What is the age of people who have Chills when taking Uniphyl? *

What are other drugs people take besides Uniphyl? *

What are other side effects people have besides Chills? *

Dyspnea (difficult or laboured breathing): 19 people, 55.88%
Nasopharyngitis (inflammation of the nasopharynx): 17 people, 50.00%
Wheezing (a high-pitched whistling sound made while you breath): 16 people, 47.06%
High Blood Pressure: 15 people, 44.12%
Fatigue (feeling of tiredness): 15 people, 44.12%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 13 people, 38.24%
Pneumonia: 12 people, 35.29%
Asthma: 12 people, 35.29%
Cough: 12 people, 35.29%
Joint Pain: 10 people, 29.41%

What are the existing conditions these people have? *

Asthma: 22 people, 64.71%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 11.76%
Cough: 3 people, 8.82%
Bronchitis Chronic (inflammation of the mucous membrane in the bronchial tubes- chronic): 3 people, 8.82%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 3 people, 8.82%
Osteoporosis (bones weak and more likely to break): 1 person, 2.94%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 1 person, 2.94%
High Blood Pressure: 1 person, 2.94%
Hepatitis C: 1 person, 2.94%
Diabetes: 1 person, 2.94%

* Approximation only. Some reports may have incomplete information.

Do you take Uniphyl and have Chills?

- Check whether Chills is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Uniphyl:

Uniphyl (3,086 reports)

Chills treatments and more:

Chills (145,628 reports)

Browse all side effects of Uniphyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Chills:

Chills (2,554 drugs)

Browse all the conditions that are associated with Chills:

Chills (3,475 conditions)

Related publications that referenced our studies

Korang-Yeboah M, Rahman Z, Shah D, Mohammad A, Wu S, Siddiqui A, Khan MA, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International journal of pharmaceutics, 2016 Feb .
Dhaval MK, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International Journal of Pharmaceutics, 2016 Jan .
Korang-Yeboah M, Rahman Z, Shah D, Mohammad A, Wu S, Siddiqui A, Khan MA, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International journal of pharmaceutics, 2016 Feb .
Dhaval MK, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International Journal of Pharmaceutics, 2016 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on theophylline (the active ingredients of Uniphyl) and Uniphyl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.