Ursodeoxycholic acid and Myositis - a phase IV clinical study of FDA data

Summary:

Myositis is reported as a side effect among people who take Ursodeoxycholic acid (ursodiol), especially for people who are female, 60+ old, also take Omeprazole, and have Crohn's disease.

The phase IV clinical study analyzes which people have Myositis when taking Ursodeoxycholic acid. It is created by eHealthMe based on reports of 7,467 people who have side effects when taking Ursodeoxycholic acid from the FDA, and is updated regularly.

What is Ursodeoxycholic acid?

Ursodeoxycholic acid has active ingredients of ursodiol. It is often used in biliary cirrhosis primary. eHealthMe is studying from 7,528 Ursodeoxycholic acid users. Check the latest studies of Ursodeoxycholic acid.

What is Myositis?

Myositis (inflammation of the muscles) is found to be associated with 827 drugs and 1,138 conditions by eHealthMe. Check the latest studies of Myositis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

7,467 people reported to have side effects when taking Ursodeoxycholic acid.
Among them, 27 people (0.36%) have Myositis.

Could Ursodeoxycholic acid cause Myositis?

Among these 27 people:

What is the gender of people who have Myositis when taking Ursodeoxycholic acid? *

female: 92.59 %
male: 7.41 %

What is the age of people who have Myositis when taking Ursodeoxycholic acid? *

What are other drugs people take besides Ursodeoxycholic acid? *

What are other side effects people have besides Myositis? *

Hepatitis Cholestatic (flow of bile from the liver is slowed or blocked): 7 people, 25.93%
Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 7 people, 25.93%
Cholecystitis Acute (rapid infection of gallbladder): 7 people, 25.93%
Alanine Aminotransferase Increased: 6 people, 22.22%
Weakness: 6 people, 22.22%
Gamma-Glutamyltransferase Increased: 6 people, 22.22%
Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 6 people, 22.22%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 6 people, 22.22%
Blood Alkaline Phosphatase Increased: 5 people, 18.52%
Blood Bilirubin Increased: 5 people, 18.52%

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 8 people, 29.63%
Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 7 people, 25.93%
Renal Cell Carcinoma (a kidney cancer): 7 people, 25.93%
Type 2 Diabetes: 5 people, 18.52%
High Blood Pressure: 4 people, 14.81%
Pain: 2 people, 7.41%
Migraine (headache): 2 people, 7.41%
Metastases To Bone (cancer spreads to bone): 2 people, 7.41%
Lung Cancer - Non-Small Cell (lung cancer): 2 people, 7.41%
Insomnia (sleeplessness): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Ursodeoxycholic acid and have Myositis?

- Check whether Myositis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ursodeoxycholic acid:

Ursodeoxycholic acid (7,528 reports)

Myositis treatments and more:

Myositis (13,181 reports)

Browse all side effects of Ursodeoxycholic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Myositis:

Myositis (827 drugs)

Browse all the conditions that are associated with Myositis:

Myositis (1,138 conditions)

Related publications that referenced our studies

Proti? D, Balti? S, Stupar N, Pavlov-Dolijanovi? S, Mugo?a S, Todorovi? Z, "A case of myositis with immunological background associated with statin use", Open Medicine, 2014 Oct .
Proti? D, Balti? S, Stupar N, Pavlov-Dolijanovi? S, Mugo?a S, Todorovi? Z, "A case of myositis with immunological background associated with statin use", Open Medicine, 2014 Oct .

How the study uses the data?

The study uses data from the FDA. It is based on ursodiol (the active ingredients of Ursodeoxycholic acid) and Ursodeoxycholic acid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.