Ursodiol and Rebound effect - a phase IV clinical study of FDA data

Summary:

Rebound effect is reported as a side effect among people who take Ursodiol (ursodiol), especially for people who are female, 40-49 old, also take Mycophenolate Mofetil, and have Hepatitis.

The phase IV clinical study analyzes which people have Rebound effect when taking Ursodiol. It is created by eHealthMe based on reports of 18,820 people who have side effects when taking Ursodiol from the FDA, and is updated regularly.

What is Ursodiol?

Ursodiol has active ingredients of ursodiol. It is often used in primary biliary cirrhosis. eHealthMe is studying from 19,061 Ursodiol users. Check the latest studies of Ursodiol.

What is Rebound effect?

Rebound effect (take-back effect) is found to be associated with 368 drugs and 569 conditions by eHealthMe. Check the latest studies of Rebound effect.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

18,820 people reported to have side effects when taking Ursodiol.
Among them, 12 people (0.06%) have Rebound effect.

Among these 12 people:

What is the gender of people who have Rebound effect when taking Ursodiol? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Rebound effect when taking Ursodiol? *

What are other drugs people take besides Ursodiol? *

What are other side effects people have besides Rebound effect? *

Presyncope: 2 people, 16.67%
Pneumonia: 2 people, 16.67%
Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 2 people, 16.67%
Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 2 people, 16.67%
Hepatitis (inflammation of the liver): 2 people, 16.67%
Hallucination, Visual (seeing things that aren't there): 2 people, 16.67%
Drug-Induced Liver Injury (diseases of the liver that are caused by physician-prescribed medications): 2 people, 16.67%
Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 2 people, 16.67%
Sinus Arrhythmia (a naturally occurring variation in heart rate that occurs during a breathing cycle): 1 person, 8.33%
Orthostatic Heart Rate Response Increased: 1 person, 8.33%

What are the existing conditions these people have? *

Pneumonia: 4 people, 33.33%
Hepatitis (inflammation of the liver): 4 people, 33.33%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 3 people, 25.00%
Epstein-Barr Virus Infection: 3 people, 25.00%
Metastases To Bone (cancer spreads to bone): 2 people, 16.67%
Lung Squamous Cell Carcinoma Stage Iii (lung cancer has spread to lymph nodes on the same side of the chest as the tumour. the lymph nodes with cancer are near the sternum (chest bone) or where the bronchus enters the lung): 2 people, 16.67%
Lung Adenocarcinoma Stage Iv (the cancer has spread to other organs of the body, such as the other lung, brain, or liver): 2 people, 16.67%
Liver Injury: 2 people, 16.67%
Iron Deficiency Anaemia: 1 person, 8.33%
Interstitial Nephritis (inflammation of the kidney): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Ursodiol and have Rebound effect?

- Check whether Rebound effect is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ursodiol:

Ursodiol (19,061 reports)

Rebound effect treatments and more:

Rebound effect (8,859 reports)

Browse all side effects of Ursodiol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rebound effect:

Rebound effect (368 drugs)

Browse all the conditions that are associated with Rebound effect:

Rebound effect (569 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ursodiol (the active ingredients of Ursodiol) and Ursodiol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.