Vagifem and Vision blurred - a phase IV clinical study of FDA data

Summary:

Vision blurred is reported as a side effect among people who take Vagifem (estradiol), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Synthroid, and have Pain.

The phase IV clinical study analyzes which people have Vision blurred when taking Vagifem. It is created by eHealthMe based on reports of 5,963 people who have side effects when taking Vagifem from the FDA, and is updated regularly.

What is Vagifem?

Vagifem has active ingredients of estradiol. It is often used in vulvovaginal dryness. eHealthMe is studying from 6,263 Vagifem users. Check the latest studies of Vagifem.

What is Vision blurred?

Vision blurred is found to be associated with 2,494 drugs and 2,969 conditions by eHealthMe. Check the latest studies of Vision blurred.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

5,963 people reported to have side effects when taking Vagifem.
Among them, 75 people (1.26%) have Vision blurred.

Among these 75 people:

How long have people been on Vagifem when they have Vision blurred? *

What is the gender of people who have Vision blurred when taking Vagifem? *

female: 98.61 %
male: 1.39 %

What is the age of people who have Vision blurred when taking Vagifem? *

What are other drugs people take besides Vagifem? *

Synthroid: 17 people, 22.67%
Calcium: 12 people, 16.00%
Amlodipine: 11 people, 14.67%
Cymbalta: 9 people, 12.00%
Toradol: 8 people, 10.67%
Vortioxetine Hydrobromide: 7 people, 9.33%
Escitalopram: 7 people, 9.33%
Prevacid: 7 people, 9.33%
Biotin: 7 people, 9.33%
Fish Oil: 6 people, 8.00%

What are other side effects people have besides Vision blurred? *

Dizziness: 19 people, 25.33%
Fatigue (feeling of tiredness): 18 people, 24.00%
Dyspnea (difficult or laboured breathing): 14 people, 18.67%
Headache (pain in head): 14 people, 18.67%
Cough: 13 people, 17.33%
Nausea (feeling of having an urge to vomit): 13 people, 17.33%
Malaise (a feeling of general discomfort or uneasiness): 12 people, 16.00%
Memory Loss: 11 people, 14.67%
High Blood Pressure: 10 people, 13.33%
Nasopharyngitis (inflammation of the nasopharynx): 10 people, 13.33%

What are the existing conditions these people have? *

Pain: 12 people, 16.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 8.00%
Depression: 4 people, 5.33%
High Blood Pressure: 4 people, 5.33%
Hypersensitivity: 4 people, 5.33%
Dry Eyes (lack of adequate tears): 4 people, 5.33%
High Blood Cholesterol: 3 people, 4.00%
Atrophic Vulvovaginitis (inflammation of the vulva): 3 people, 4.00%
Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 3 people, 4.00%
Sleep Disorder: 2 people, 2.67%

* Approximation only. Some reports may have incomplete information.

Do you take Vagifem and have Vision blurred?

- Check whether Vision blurred is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vagifem:

Vagifem (6,263 reports)

Vision blurred treatments and more:

Vision blurred (154,118 reports)

Browse all side effects of Vagifem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Vision blurred:

Vision blurred (2,494 drugs)

Browse all the conditions that are associated with Vision blurred:

Vision blurred (2,969 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on estradiol (the active ingredients of Vagifem) and Vagifem (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.