Valacyclovir hydrochloride and Peripheral coldness - a phase IV clinical study of FDA data

Summary:

Peripheral coldness is reported as a side effect among people who take Valacyclovir hydrochloride (valacyclovir hydrochloride), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Amlodipine Besylate, and have Cataplexy.

The phase IV clinical study analyzes which people have Peripheral coldness when taking Valacyclovir hydrochloride. It is created by eHealthMe based on reports of 12,770 people who have side effects when taking Valacyclovir hydrochloride from the FDA, and is updated regularly.

What is Valacyclovir hydrochloride?

Valacyclovir hydrochloride has active ingredients of valacyclovir hydrochloride. It is often used in herpes zoster. eHealthMe is studying from 12,929 Valacyclovir hydrochloride users. Check the latest studies of Valacyclovir hydrochloride.

What is Peripheral coldness?

Peripheral coldness is found to be associated with 1,076 drugs and 1,154 conditions by eHealthMe. Check the latest studies of Peripheral coldness.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

12,770 people reported to have side effects when taking Valacyclovir hydrochloride.
Among them, 16 people (0.13%) have Peripheral coldness.

Could Valacyclovir hydrochloride cause Peripheral coldness?

Among these 16 people:

How long have people been on Valacyclovir hydrochloride when they have Peripheral coldness? *

What is the gender of people who have Peripheral coldness when taking Valacyclovir hydrochloride? *

female: 75 %
male: 25 %

What is the age of people who have Peripheral coldness when taking Valacyclovir hydrochloride? *

What are other drugs people take besides Valacyclovir hydrochloride? *

Amlodipine Besylate: 5 people, 31.25%
Adderall: 4 people, 25.00%
Xyrem: 4 people, 25.00%
Eliquis: 4 people, 25.00%
Minocycline Hydrochloride: 4 people, 25.00%
Sunosi: 4 people, 25.00%
Pregabalin: 3 people, 18.75%
Cetirizine Hydrochloride: 3 people, 18.75%
Effexor: 3 people, 18.75%
Eltrombopag Olamine: 3 people, 18.75%

What are other side effects people have besides Peripheral coldness? *

Dyspnea (difficult or laboured breathing): 8 people, 50.00%
Diarrhea: 7 people, 43.75%
Oral Herpes (viral infection of mouth): 6 people, 37.50%
Hypoaesthesia (reduced sense of touch or sensation): 5 people, 31.25%
Abdominal Pain: 5 people, 31.25%
Joint Pain: 5 people, 31.25%
Weakness: 4 people, 25.00%
Hepatic Vein Thrombosis (obstruction in the veins of the liver caused by a blood clot): 4 people, 25.00%
Nausea And Vomiting: 4 people, 25.00%
Appetite - Increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires): 4 people, 25.00%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 31.25%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 31.25%
Pain: 4 people, 25.00%
Drowsiness: 4 people, 25.00%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 3 people, 18.75%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 3 people, 18.75%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 12.50%
Asthma: 2 people, 12.50%
Multiple Myeloma (cancer of the plasma cells): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Valacyclovir hydrochloride and have Peripheral coldness?

- Check whether Peripheral coldness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Valacyclovir hydrochloride:

Valacyclovir hydrochloride (12,929 reports)

Browse all side effects of Valacyclovir hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Peripheral coldness:

Peripheral coldness (1,076 drugs)

Browse all the conditions that are associated with Peripheral coldness:

Peripheral coldness (1,154 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on valacyclovir hydrochloride (the active ingredients of Valacyclovir hydrochloride) and Valacyclovir hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.