Valacyclovir and Brain oedema - a phase IV clinical study of FDA data
Summary:
Brain oedema is reported as a side effect among people who take Valacyclovir (valacyclovir hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Furosemide, and have Hodgkin's lymphoma.
The phase IV clinical study analyzes which people have Brain oedema when taking Valacyclovir. It is created by eHealthMe based on reports of 41,259 people who have side effects when taking Valacyclovir from the FDA, and is updated regularly.
What is Valacyclovir?
Valacyclovir has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 42,107 Valacyclovir users. Check the latest studies of Valacyclovir.
What is Brain oedema?
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain) is found to be associated with 966 drugs and 1,252 conditions by eHealthMe. Check the latest studies of Brain oedema.
41,259 people reported to have side effects when taking Valacyclovir.
Among them, 25 people (0.06%) have Brain oedema.

Among these 25 people:
How long have people been on Valacyclovir when they have Brain oedema? *
- < 1 month: 100 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Brain oedema when taking Valacyclovir? *
- female: 66.67 %
- male: 33.33 %
What is the age of people who have Brain oedema when taking Valacyclovir? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 5 %
- 20-29: 15 %
- 30-39: 0.0 %
- 40-49: 10 %
- 50-59: 15 %
- 60+: 55 %
What are other drugs people take besides Valacyclovir? *
- Cyclosporine: 8 people, 32.00%
- Furosemide: 8 people, 32.00%
- Heparin: 7 people, 28.00%
- Tranexamic Acid: 7 people, 28.00%
- Morphine Sulfate: 7 people, 28.00%
- Pregabalin: 7 people, 28.00%
- Fluconazole: 7 people, 28.00%
- Meropenem: 7 people, 28.00%
- Ursodiol: 7 people, 28.00%
- Lansoprazole: 7 people, 28.00%
What are other side effects people have besides Brain oedema? *
- Headache (pain in head): 4 people, 16.00%
- Thrombocytopenia (decrease of platelets in blood): 3 people, 12.00%
- Cerebral Haemorrhage (bleeding within the brain): 3 people, 12.00%
- Brain Death: 3 people, 12.00%
- Arteriosclerosis Coronary Artery (thickening and hardening of arteries- coronary artery): 2 people, 8.00%
- Live Birth: 2 people, 8.00%
- Intracranial Pressure Increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid): 2 people, 8.00%
- Disseminated Cytomegaloviral Infection (group of herpes viruses infection): 2 people, 8.00%
- Impaired Healing: 2 people, 8.00%
- Cerebral Venous Thrombosis (clot in brains venous blood system): 2 people, 8.00%
What are the existing conditions these people have? *
- Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 2 people, 8.00%
- Bone Marrow Conditioning Regimen: 2 people, 8.00%
- Colitis (inflammation of colon): 2 people, 8.00%
- Muscle Aches (muscle pain): 2 people, 8.00%
- Disseminated Cytomegaloviral Infection (group of herpes viruses infection): 2 people, 8.00%
- Enterocolitis Haemorrhagic (bleeding and inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon): 2 people, 8.00%
- Hodgkin's Lymphoma (cancer originating from white blood cells): 2 people, 8.00%
- Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 1 person, 4.00%
- Combined Immunodeficiency: 1 person, 4.00%
- Constipation: 1 person, 4.00%
* Approximation only. Some reports may have incomplete information.
Do you take Valacyclovir and have Brain oedema?
- Check whether Brain oedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Valacyclovir:
- Valacyclovir (42,107 reports)
Brain oedema treatments and more:
- Brain oedema (16,340 reports)
How severe was Brain oedema and when was it recovered:
Expand to all the drugs that have ingredients of valacyclovir hydrochloride:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Valacyclovir:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Brain oedema:
- Brain oedema (966 drugs)
Browse all the conditions that are associated with Brain oedema:
- Brain oedema (1,252 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on valacyclovir hydrochloride (the active ingredients of Valacyclovir) and Valacyclovir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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