Valcyte and C. diff - a phase IV clinical study of FDA data

Summary:

C. diff is reported as a side effect among people who take Valcyte (valganciclovir hydrochloride), especially for people who are male, 50-59 old, have been taking the drug for 1 - 6 months also take Bactrim, and have Cytomegalovirus infection.

The phase IV clinical study analyzes which people have C. diff when taking Valcyte. It is created by eHealthMe based on reports of 6,369 people who have side effects when taking Valcyte from the FDA, and is updated regularly.

What is Valcyte?

Valcyte has active ingredients of valganciclovir hydrochloride. It is often used in cmv - immunocompromised host. eHealthMe is studying from 6,409 Valcyte users. Check the latest studies of Valcyte.

What is C. diff?

C. diff is found to be associated with 1,625 drugs and 1,768 conditions by eHealthMe. Check the latest studies of C. diff.

On Dec, 27, 2025

6,369 people reported to have side effects when taking Valcyte.
Among them, 47 people (0.74%) have C. diff.

Among these 47 people:

How long have people been on Valcyte when they have C. diff? *

What is the gender of people who have C. diff when taking Valcyte? *

female: 24.44 %
male: 75.56 %

What is the age of people who have C. diff when taking Valcyte? *

What are other drugs people take besides Valcyte? *

Bactrim: 20 people, 42.55%
Mycophenolate Mofetil: 18 people, 38.30%
Pepcid: 17 people, 36.17%
Protonix: 15 people, 31.91%
Ultram: 14 people, 29.79%
Atarax: 14 people, 29.79%
Prevacid: 14 people, 29.79%
Acyclovir: 14 people, 29.79%
Tacrolimus: 11 people, 23.40%
Sirolimus: 9 people, 19.15%

What are other side effects people have besides C. diff? *

Upper Respiratory Tract Infection: 15 people, 31.91%
Liver Transplant Rejection (failure of liver transplant): 14 people, 29.79%
Cholangitis (infection of the bile duct): 14 people, 29.79%
Thrombosis (formation of a blood clot inside a blood vessel): 14 people, 29.79%
Dyspnea (difficult or laboured breathing): 12 people, 25.53%
Abdominal Pain Upper: 11 people, 23.40%
Bile Duct Obstruction (blockage in the tubes that carry bile from the liver to the gallbladder): 10 people, 21.28%
Nausea (feeling of having an urge to vomit): 10 people, 21.28%
Fever: 9 people, 19.15%
Cough: 8 people, 17.02%

What are the existing conditions these people have? *

Cytomegalovirus Infection: 7 people, 14.89%
Diarrhea: 4 people, 8.51%
Nausea (feeling of having an urge to vomit): 4 people, 8.51%
Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 3 people, 6.38%
Immunodeficiency Disorders: 3 people, 6.38%
Blood Testosterone Decreased: 2 people, 4.26%
Pain: 2 people, 4.26%
Oedema (fluid collection in tissue): 2 people, 4.26%
High Blood Pressure: 2 people, 4.26%
Urinary Tract Infection Viral: 2 people, 4.26%

* Approximation only. Some reports may have incomplete information.

Do you take Valcyte and have C. diff?

- Check whether C. diff is associated with a drug or a condition (FREE)
- Predict drug outcomes for up to one year with AI (FREE)
- Get an AI agent to monitor your drugs continuously (FREE)

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Valcyte:

Valcyte (6,409 reports)

C. diff treatments and more:

C. diff (13,844 reports)

Browse all side effects of Valcyte:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with C. diff:

C. diff (1,625 drugs)

Browse all the conditions that are associated with C. diff:

C. diff (1,768 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on valganciclovir hydrochloride (the active ingredients of Valcyte) and Valcyte (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.