Valproate sodium and Bradykinesia - a phase IV clinical study of FDA data

Summary:

Bradykinesia is reported as a side effect among people who take Valproate sodium (valproate sodium), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Olanzapine, and have Hypothyroidism.

The phase IV clinical study analyzes which people have Bradykinesia when taking Valproate sodium. It is created by eHealthMe based on reports of 23,476 people who have side effects when taking Valproate sodium from the FDA, and is updated regularly.

What is Valproate sodium?

Valproate sodium has active ingredients of valproate sodium. It is often used in epilepsy. eHealthMe is studying from 24,044 Valproate sodium users. Check the latest studies of Valproate sodium.

What is Bradykinesia?

Bradykinesia (decreased bodily movement. it is associated with basal ganglia diseases) is found to be associated with 429 drugs and 471 conditions by eHealthMe. Check the latest studies of Bradykinesia.



On Jul, 21, 2026

23,476 people reported to have side effects when taking Valproate sodium.
Among them, 53 people (0.23%) have Bradykinesia.

Could Valproate sodium cause Bradykinesia?

Among these 53 people:

How long have people been on Valproate sodium when they have Bradykinesia? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Bradykinesia when taking Valproate sodium? *

  • female: 38.46 %
  • male: 61.54 %

What is the age of people who have Bradykinesia when taking Valproate sodium? *

  • 0-1: 2.27 %
  • 2-9: 0.0 %
  • 10-19: 6.82 %
  • 20-29: 6.82 %
  • 30-39: 9.09 %
  • 40-49: 20.45 %
  • 50-59: 15.91 %
  • 60+: 38.64 %

What are other drugs people take besides Valproate sodium? *

  1. Folic Acid: 9 people, 16.98%
  2. Olanzapine: 9 people, 16.98%
  3. Amantadine: 7 people, 13.21%
  4. Valproic Acid: 6 people, 11.32%
  5. Levothyroxine Sodium: 6 people, 11.32%
  6. Lorazepam: 6 people, 11.32%
  7. Valium: 4 people, 7.55%
  8. Seroquel: 4 people, 7.55%
  9. Lithium Carbonate: 4 people, 7.55%
  10. Clonazepam: 4 people, 7.55%

What are other side effects people have besides Bradykinesia? *

  1. Muscle Rigidity (muscle stiffness): 19 people, 35.85%
  2. Drowsiness: 17 people, 32.08%
  3. Tremor (trembling or shaking movements in one or more parts of your body): 14 people, 26.42%
  4. Fatigue (feeling of tiredness): 13 people, 24.53%
  5. Memory Loss: 12 people, 22.64%
  6. Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 12 people, 22.64%
  7. Gait Disturbance: 11 people, 20.75%
  8. Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 11 people, 20.75%
  9. Dysmorphism (difference of body structure that is suggestive of a congenital disorder): 10 people, 18.87%
  10. Dehydration (dryness resulting from the removal of water): 10 people, 18.87%

What are the existing conditions these people have? *

  1. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 15.09%
  2. Psychotic Disorder: 7 people, 13.21%
  3. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 9.43%
  4. Suicide Attempt: 3 people, 5.66%
  5. Affective Disorder (mental disorder): 3 people, 5.66%
  6. Partial Seizures (seizures which affect only a part of the brain at onset): 2 people, 3.77%
  7. Mania (a state of abnormally elevated or irritable mood): 2 people, 3.77%
  8. Grand Mal Convulsion (a type of generalized seizure that affects the entire brain): 2 people, 3.77%
  9. Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 2 people, 3.77%
  10. Depression: 2 people, 3.77%

* Approximation only. Some reports may have incomplete information.

Do you take Valproate sodium and have Bradykinesia?

- Check whether Bradykinesia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Valproate sodium:

Bradykinesia treatments and more:

How severe was Bradykinesia and when was it recovered:

Expand to all the drugs that have ingredients of valproate sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Valproate sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bradykinesia:

Browse all the conditions that are associated with Bradykinesia:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on valproate sodium (the active ingredients of Valproate sodium) and Valproate sodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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