Valproate sodium and Hepatic enzyme increased - a phase IV clinical study of FDA data

Summary:

Hepatic enzyme increased is reported as a side effect among people who take Valproate sodium (valproate sodium), especially for people who are male, 20-29 old, have been taking the drug for < 1 month also take Lamotrigine, and have Seizures.

The phase IV clinical study analyzes which people have Hepatic enzyme increased when taking Valproate sodium. It is created by eHealthMe based on reports of 23,476 people who have side effects when taking Valproate sodium from the FDA, and is updated regularly.

What is Valproate sodium?

Valproate sodium has active ingredients of valproate sodium. It is often used in epilepsy. eHealthMe is studying from 24,044 Valproate sodium users. Check the latest studies of Valproate sodium.

What is Hepatic enzyme increased?

Hepatic enzyme increased is found to be associated with 1,885 drugs and 2,014 conditions by eHealthMe. Check the latest studies of Hepatic enzyme increased.

On Jul, 19, 2026

23,476 people reported to have side effects when taking Valproate sodium.
Among them, 151 people (0.64%) have Hepatic enzyme increased.

Could Valproate sodium cause Hepatic enzyme increased?

Among these 151 people:

How long have people been on Valproate sodium when they have Hepatic enzyme increased? *

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What is the gender of people who have Hepatic enzyme increased when taking Valproate sodium? *

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What is the age of people who have Hepatic enzyme increased when taking Valproate sodium? *

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* Approximation only. Some reports may have incomplete information.

Do you take Valproate sodium and have Hepatic enzyme increased?

- Check whether Hepatic enzyme increased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Valproate sodium:

Valproate sodium (24,044 reports)

Hepatic enzyme increased treatments and more:

Hepatic enzyme increased (74,970 reports)

How severe was Hepatic enzyme increased and when was it recovered:

Hepatic enzyme increased in Valproate sodium

Expand to all the drugs that have ingredients of valproate sodium:

Hepatic enzyme increased and drugs with ingredients of valproate sodium (90 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Valproate sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatic enzyme increased:

Hepatic enzyme increased (1,885 drugs)

Browse all the conditions that are associated with Hepatic enzyme increased:

Hepatic enzyme increased (2,014 conditions)

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on valproate sodium (the active ingredients of Valproate sodium) and Valproate sodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.