Valproate sodium and Pre-eclampsia - a phase IV clinical study of FDA data
Summary:
Pre-eclampsia is reported as a side effect among people who take Valproate sodium (valproate sodium), especially for people who are 20-29 old, have been taking the drug for 6 - 12 months also take Folic Acid,.
The phase IV clinical study analyzes which people have Pre-eclampsia when taking Valproate sodium. It is created by eHealthMe based on reports of 23,476 people who have side effects when taking Valproate sodium from the FDA, and is updated regularly.
What is Valproate sodium?
Valproate sodium has active ingredients of valproate sodium. It is often used in epilepsy. eHealthMe is studying from 24,044 Valproate sodium users. Check the latest studies of Valproate sodium.
What is Pre-eclampsia?
Pre-eclampsia (high blood pressure and significant amounts of protein in the urine of a pregnant woman) is found to be associated with 392 drugs and 577 conditions by eHealthMe. Check the latest studies of Pre-eclampsia.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
23,476 people reported to have side effects when taking Valproate sodium.
Among them, 17 people (0.07%) have Pre-eclampsia.

Among these 17 people:
How long have people been on Valproate sodium when they have Pre-eclampsia? *
- < 1 month: 0.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 50 %
- 1 - 2 years: 50 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the age of people who have Pre-eclampsia when taking Valproate sodium? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 75 %
- 30-39: 25 %
- 40-49: 0.0 %
- 50-59: 0.0 %
- 60+: 0.0 %
What are other drugs people take besides Valproate sodium? *
- Folic Acid: 6 people, 35.29%
- Lamictal: 4 people, 23.53%
- Prozac: 2 people, 11.76%
- Zarontin: 1 person, 5.88%
- Trandate: 1 person, 5.88%
- Oxytocin: 1 person, 5.88%
- Oxazepam: 1 person, 5.88%
- Magnesium Sulfate: 1 person, 5.88%
- Lexapro: 1 person, 5.88%
- Keppra: 1 person, 5.88%
What are other side effects people have besides Pre-eclampsia? *
- Drug Exposure During Pregnancy: 6 people, 35.29%
- Maternal Exposure During Pregnancy (use of substance during pregnancy): 3 people, 17.65%
- Stillbirth (a birth of dead foetus): 3 people, 17.65%
- Oligohydramnios (a condition in pregnancy characterized by a deficiency of amniotic fluid): 2 people, 11.76%
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 11.76%
- Thrombocytopenia (decrease of platelets in blood): 1 person, 5.88%
- Foetal Growth Restriction (poor growth of a baby while in the mother's womb during pregnancy): 1 person, 5.88%
- Abortion Spontaneous (naturally occurring miscarriage): 1 person, 5.88%
- Back Pain: 1 person, 5.88%
- Bacterial Toxaemia (blood contains bacterial toxins): 1 person, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Valproate sodium and have Pre-eclampsia?
- Check whether Pre-eclampsia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, long term effects of, and alternative drugs to Valproate sodium:
- Valproate sodium (24,044 reports)
Pre-eclampsia treatments and more:
- Pre-eclampsia (6,691 reports)
How severe was Pre-eclampsia and when was it recovered:
Expand to all the drugs that have ingredients of valproate sodium:
Sub-studies by age:
0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Valproate sodium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Pre-eclampsia:
- Pre-eclampsia (392 drugs)
Browse all the conditions that are associated with Pre-eclampsia:
- Pre-eclampsia (577 conditions)
Related publications that referenced our studies
- Ayano G, "Bipolar Disorders and Valproate: Pharmacokinetics, Pharmacodynamics and Therapeutic Effects and Indications of Valproate: Review of Articles", Bipolar Disord, 2017 Jan .
- Bansal S, Gupta SK, "Sodium Valproate induced priapism in an adult with bipolar affective disorder", Indian journal of pharmacology, 2013 Jan .
- Ayano G, "Bipolar Disorders and Valproate: Pharmacokinetics, Pharmacodynamics and Therapeutic Effects and Indications of Valproate: Review of Articles", Bipolar Disord, 2017 Jan .
- Bansal S, Gupta SK, "Sodium Valproate induced priapism in an adult with bipolar affective disorder", Indian journal of pharmacology, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on valproate sodium (the active ingredients of Valproate sodium) and Valproate sodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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