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Valproate sodium and Surgery - a phase IV clinical study of FDA data

Summary:

Surgery is reported as a side effect among people who take Valproate sodium (valproate sodium), especially for people who are female, 40-49 old, also take Clozaril, and have Schizophrenia.

The phase IV clinical study analyzes which people have Surgery when taking Valproate sodium. It is created by eHealthMe based on reports of 23,476 people who have side effects when taking Valproate sodium from the FDA, and is updated regularly.

What is Valproate sodium?

Valproate sodium has active ingredients of valproate sodium. It is often used in epilepsy. eHealthMe is studying from 24,044 Valproate sodium users. Check the latest studies of Valproate sodium.

What is Surgery?

Surgery is found to be associated with 1,480 drugs and 1,244 conditions by eHealthMe. Check the latest studies of Surgery.

On Jul, 07, 2026

23,476 people reported to have side effects when taking Valproate sodium.
Among them, 36 people (0.15%) have Surgery.

Could Valproate sodium cause Surgery?

Among these 36 people:

What is the gender of people who have Surgery when taking Valproate sodium? *

  • female: 57.58 %
  • male: 42.42 %

What is the age of people who have Surgery when taking Valproate sodium? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 25.0 %
  • 40-49: 33.33 %
  • 50-59: 25.0 %
  • 60+: 16.67 %

What are other drugs people take besides Valproate sodium? *

  1. Clozaril: 12 people, 33.33%
  2. Irbesartan: 3 people, 8.33%
  3. Nplate: 3 people, 8.33%
  4. Atenolol: 3 people, 8.33%
  5. Desmopressin Acetate: 3 people, 8.33%
  6. Lamictal: 3 people, 8.33%
  7. Cyclophosphamide: 2 people, 5.56%
  8. Carisoprodol: 2 people, 5.56%
  9. Lithium Carbonate: 2 people, 5.56%
  10. Ibuprofen: 2 people, 5.56%

What are other side effects people have besides Surgery? *

  1. Thrombocytopenia (decrease of platelets in blood): 12 people, 33.33%
  2. Malaise (a feeling of general discomfort or uneasiness): 7 people, 19.44%
  3. Stress And Anxiety: 5 people, 13.89%
  4. Constipation: 5 people, 13.89%
  5. Weight Decreased: 4 people, 11.11%
  6. Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs): 4 people, 11.11%
  7. Nausea And Vomiting: 4 people, 11.11%
  8. Haemoglobin Decreased: 4 people, 11.11%
  9. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 4 people, 11.11%
  10. White Blood Cell Count Increased: 3 people, 8.33%

What are the existing conditions these people have? *

  1. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 10 people, 27.78%
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 3 people, 8.33%
  3. Ill-Defined Disorder: 2 people, 5.56%
  4. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 2.78%
  5. Salivary Hypersecretion (excess saliva secretion): 1 person, 2.78%
  6. Oedema (fluid collection in tissue): 1 person, 2.78%
  7. Diabetes: 1 person, 2.78%
  8. Affective Disorder (mental disorder): 1 person, 2.78%

* Approximation only. Some reports may have incomplete information.

Do you take Valproate sodium and have Surgery?

- Check whether Surgery is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Valproate sodium:

Surgery treatments and more:

How severe was Surgery and when was it recovered:

Expand to all the drugs that have ingredients of valproate sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Valproate sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Surgery:

Browse all the conditions that are associated with Surgery:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on valproate sodium (the active ingredients of Valproate sodium) and Valproate sodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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