Valproic acid and Bronchospasm - a phase IV clinical study of FDA data

Summary:

Bronchospasm is reported as a side effect among people who take Valproic acid (valproic acid), especially for people who are male, 2-9 old, have been taking the drug for < 1 month also take Lamictal, and have Asthma.

The phase IV clinical study analyzes which people have Bronchospasm when taking Valproic acid. It is created by eHealthMe based on reports of 35,830 people who have side effects when taking Valproic acid from the FDA, and is updated regularly.

What is Valproic acid?

Valproic acid has active ingredients of valproic acid. It is often used in epilepsy. eHealthMe is studying from 36,193 Valproic acid users. Check the latest studies of Valproic acid.

What is Bronchospasm?

Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi) is found to be associated with 1,121 drugs and 1,099 conditions by eHealthMe. Check the latest studies of Bronchospasm.



On Jul, 31, 2026

35,830 people reported to have side effects when taking Valproic acid.
Among them, 12 people (0.03%) have Bronchospasm.

Could Valproic acid cause Bronchospasm?

Among these 12 people:

How long have people been on Valproic acid when they have Bronchospasm? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Bronchospasm when taking Valproic acid? *

  • female: 18.18 %
  • male: 81.82 %

What is the age of people who have Bronchospasm when taking Valproic acid? *

  • 0-1: 0.0 %
  • 2-9: 40 %
  • 10-19: 30 %
  • 20-29: 10 %
  • 30-39: 0.0 %
  • 40-49: 10 %
  • 50-59: 0.0 %
  • 60+: 10 %

What are other drugs people take besides Valproic acid? *

  1. Carbamazepine: 2 people, 16.67%
  2. Lamictal: 2 people, 16.67%
  3. Zyprexa Zydis: 1 person, 8.33%
  4. Lorazepam: 1 person, 8.33%
  5. Atrovent: 1 person, 8.33%
  6. Clobazam: 1 person, 8.33%
  7. Clonazepam: 1 person, 8.33%
  8. Dalmane: 1 person, 8.33%
  9. Elaprase: 1 person, 8.33%
  10. Geodon: 1 person, 8.33%

What are other side effects people have besides Bronchospasm? *

  1. Fever: 4 people, 33.33%
  2. Pneumonia: 3 people, 25.00%
  3. Fatigue (feeling of tiredness): 3 people, 25.00%
  4. Dyspnea (difficult or laboured breathing): 3 people, 25.00%
  5. Cough: 3 people, 25.00%
  6. Pulmonary Congestion (congestion in the lungs): 2 people, 16.67%
  7. Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 2 people, 16.67%
  8. Skin Blushing/flushing (a sudden reddening of the face, neck): 2 people, 16.67%
  9. Nausea (feeling of having an urge to vomit): 2 people, 16.67%
  10. Rashes (redness): 2 people, 16.67%

What are the existing conditions these people have? *

  1. Schizoaffective Disorder (a mental disorder characterized by disordered thought): 1 person, 8.33%
  2. Pneumonia: 1 person, 8.33%
  3. Movement - Uncontrolled Or Slow: 1 person, 8.33%
  4. Idiopathic Pulmonary Fibrosis (chronic lung disease): 1 person, 8.33%
  5. Hypertrophic Cardiomyopathy (a condition in which the heart muscle becomes abnormally thick): 1 person, 8.33%
  6. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 8.33%
  7. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 8.33%
  8. Bronchopulmonary Dysplasia (chronic lung disorder in infants - enlargement of an organ or tissue by the proliferation of cells of an abnormal type): 1 person, 8.33%
  9. Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 1 person, 8.33%
  10. Asthma: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Valproic acid and have Bronchospasm?

- Check whether Bronchospasm is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Valproic acid:

Bronchospasm treatments and more:

How severe was Bronchospasm and when was it recovered:

Expand to all the drugs that have ingredients of valproic acid:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Valproic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bronchospasm:

Browse all the conditions that are associated with Bronchospasm:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on valproic acid (the active ingredients of Valproic acid) and Valproic acid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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