Valsartan and Breakthrough pain - a phase IV clinical study of FDA data

Summary:

Breakthrough pain is reported as a side effect among people who take Valsartan (valsartan), especially for people who are male, 60+ old, also take Enzalutamide,.

The phase IV clinical study analyzes which people have Breakthrough pain when taking Valsartan. It is created by eHealthMe based on reports of 62,763 people who have side effects when taking Valsartan from the FDA, and is updated regularly.

What is Valsartan?

Valsartan has active ingredients of valsartan. It is often used in high blood pressure. eHealthMe is studying from 63,805 Valsartan users. Check the latest studies of Valsartan.

What is Breakthrough pain?

Breakthrough pain is found to be associated with 271 drugs and 417 conditions by eHealthMe. Check the latest studies of Breakthrough pain.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

62,763 people reported to have side effects when taking Valsartan.
Among them, 11 people (0.02%) have Breakthrough pain.

Could Valsartan cause Breakthrough pain?

Among these 11 people:

What is the gender of people who have Breakthrough pain when taking Valsartan? *

female: 11.11 %
male: 88.89 %

What is the age of people who have Breakthrough pain when taking Valsartan? *

What are other drugs people take besides Valsartan? *

What are other side effects people have besides Breakthrough pain? *

Pain: 10 people, 90.91%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 10 people, 90.91%
Anaemia (lack of blood): 10 people, 90.91%
Metastasis (spreadable cancer to other organ from origin): 8 people, 72.73%
Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue): 8 people, 72.73%
Prostatic Specific Antigen Increased: 2 people, 18.18%
Prostate Cancer: 2 people, 18.18%
Malignant Neoplasm Progression (cancer tumour came back): 2 people, 18.18%
Dyspnea (difficult or laboured breathing): 1 person, 9.09%
Drowsiness: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Valsartan and have Breakthrough pain?

- Check whether Breakthrough pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Valsartan:

Valsartan (63,805 reports)

Browse all side effects of Valsartan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Breakthrough pain:

Breakthrough pain (271 drugs)

Browse all the conditions that are associated with Breakthrough pain:

Breakthrough pain (417 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on valsartan (the active ingredients of Valsartan) and Valsartan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.