Vasotec and Gangrene - a phase IV clinical study of FDA data

Summary:

Gangrene is reported as a side effect among people who take Vasotec (enalapril maleate), especially for people who are male, 40-49 old, also take Coreg, and have Cardiac failure congestive.

The phase IV clinical study analyzes which people have Gangrene when taking Vasotec. It is created by eHealthMe based on reports of 14,393 people who have side effects when taking Vasotec from the FDA, and is updated regularly.

What is Vasotec?

Vasotec has active ingredients of enalapril maleate. It is often used in high blood pressure. eHealthMe is studying from 14,646 Vasotec users. Check the latest studies of Vasotec.

What is Gangrene?

Gangrene (body tissue dies) is found to be associated with 650 drugs and 721 conditions by eHealthMe. Check the latest studies of Gangrene.



On Jul, 17, 2026

14,393 people reported to have side effects when taking Vasotec.
Among them, 21 people (0.15%) have Gangrene.

Could Vasotec cause Gangrene?

Among these 21 people:

What is the gender of people who have Gangrene when taking Vasotec? *

  • female: 35 %
  • male: 65 %

What is the age of people who have Gangrene when taking Vasotec? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 16.67 %
  • 30-39: 0.0 %
  • 40-49: 44.44 %
  • 50-59: 16.67 %
  • 60+: 22.22 %

What are other drugs people take besides Vasotec? *

  1. Zyprexa: 6 people, 28.57%
  2. Niaspan: 6 people, 28.57%
  3. Coreg: 6 people, 28.57%
  4. Clonazepam: 5 people, 23.81%
  5. Lipitor: 5 people, 23.81%
  6. Lasix: 5 people, 23.81%
  7. Lantus: 5 people, 23.81%
  8. Indocin: 5 people, 23.81%
  9. Aspirin: 5 people, 23.81%
  10. Valproic Acid: 5 people, 23.81%

What are other side effects people have besides Gangrene? *

  1. Diabetes Insipidus - Nephrogenic (diabetes caused by a deficiency of the pituitary hormone vasopressin, which regulates kidney function): 5 people, 23.81%
  2. Aortic Thrombosis (formation of a blood clot inside aorta): 5 people, 23.81%
  3. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 23.81%
  4. Neuroleptic Malignant Syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents): 5 people, 23.81%
  5. Acute Kidney Failure: 5 people, 23.81%
  6. Wound Infection: 4 people, 19.05%
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 4 people, 19.05%
  8. Peripheral Vascular Disorder: 4 people, 19.05%
  9. Multi-Organ Failure (multisystem organ failure): 4 people, 19.05%
  10. Cardiogenic Shock (inadequate circulation of blood): 4 people, 19.05%

What are the existing conditions these people have? *

  1. Type 2 Diabetes: 1 person, 4.76%
  2. Psychotic Disorder: 1 person, 4.76%
  3. Poor Peripheral Circulation: 1 person, 4.76%
  4. Hypercoagulation (increased tendency for clotting of the blood): 1 person, 4.76%
  5. Cardiac Failure Congestive: 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Vasotec and have Gangrene?

- Check whether Gangrene is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vasotec:

Gangrene treatments and more:

How severe was Gangrene and when was it recovered:

Expand to all the drugs that have ingredients of enalapril maleate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vasotec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gangrene:

Browse all the conditions that are associated with Gangrene:


How the study uses the data?

The study uses data from the FDA. It is based on enalapril maleate (the active ingredients of Vasotec) and Vasotec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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