Vasotec and Pathological fracture - a phase IV clinical study of FDA data

Summary:

Pathological fracture is reported as a side effect among people who take Vasotec (enalapril maleate), especially for people who are female, 60+ old, also take Zometa, and have Metastases to bone.

The phase IV clinical study analyzes which people have Pathological fracture when taking Vasotec. It is created by eHealthMe based on reports of 14,393 people who have side effects when taking Vasotec from the FDA, and is updated regularly.

What is Vasotec?

Vasotec has active ingredients of enalapril maleate. It is often used in high blood pressure. eHealthMe is studying from 14,646 Vasotec users. Check the latest studies of Vasotec.

What is Pathological fracture?

Pathological fracture (broken bone caused by disease) is found to be associated with 836 drugs and 542 conditions by eHealthMe. Check the latest studies of Pathological fracture.

On Aug, 09, 2026

14,393 people reported to have side effects when taking Vasotec.
Among them, 51 people (0.35%) have Pathological fracture.

$Could Vasotec cause Pathological fracture?$

Among these 51 people:

What is the gender of people who have Pathological fracture when taking Vasotec? *

female: 74.51 %
male: 25.49 %

What is the age of people who have Pathological fracture when taking Vasotec? *

What are other drugs people take besides Vasotec? *

What are other side effects people have besides Pathological fracture? *

Pain: 47 people, 92.16%
Osteonecrosis Of Jaw (death of bone of jaw): 45 people, 88.24%
Stress And Anxiety: 38 people, 74.51%
Metastases To Bone (cancer spreads to bone): 32 people, 62.75%
Intervertebral Disc Degeneration (spinal disc degeneration): 31 people, 60.78%
Joint Pain: 31 people, 60.78%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 30 people, 58.82%
Weakness: 29 people, 56.86%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 29 people, 56.86%
Diarrhea: 29 people, 56.86%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 13 people, 25.49%
Metastases To Bone (cancer spreads to bone): 13 people, 25.49%
Back Pain: 8 people, 15.69%
Traumatic Injury Of The Bladder And Urethra: 5 people, 9.80%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 3.92%
Prostate Cancer: 1 person, 1.96%
Parkinson's Disease: 1 person, 1.96%
Osteoporosis (bones weak and more likely to break): 1 person, 1.96%
Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 1.96%
Metastases To Pelvis (cancer spreads to pelvis): 1 person, 1.96%

* Approximation only. Some reports may have incomplete information.

Do you take Vasotec and have Pathological fracture?

- Check whether Pathological fracture is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vasotec:

Vasotec (14,646 reports)

Browse all side effects of Vasotec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pathological fracture:

Pathological fracture (836 drugs)

Browse all the conditions that are associated with Pathological fracture:

Pathological fracture (542 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on enalapril maleate (the active ingredients of Vasotec) and Vasotec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.