Vasotec and Reflux oesophagitis - a phase IV clinical study of FDA data

Summary:

Reflux oesophagitis is reported as a side effect among people who take Vasotec (enalapril maleate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Plavix, and have Acne.

The phase IV clinical study analyzes which people have Reflux oesophagitis when taking Vasotec. It is created by eHealthMe based on reports of 14,393 people who have side effects when taking Vasotec from the FDA, and is updated regularly.

What is Vasotec?

Vasotec has active ingredients of enalapril maleate. It is often used in high blood pressure. eHealthMe is studying from 14,646 Vasotec users. Check the latest studies of Vasotec.

What is Reflux oesophagitis?

Reflux oesophagitis (an oesophageal mucosal injury that occurs of gastric contents into the oesophagus) is found to be associated with 338 drugs and 570 conditions by eHealthMe. Check the latest studies of Reflux oesophagitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

14,393 people reported to have side effects when taking Vasotec.
Among them, 13 people (0.09%) have Reflux oesophagitis.

Could Vasotec cause Reflux oesophagitis?

Among these 13 people:

How long have people been on Vasotec when they have Reflux oesophagitis? *

What is the gender of people who have Reflux oesophagitis when taking Vasotec? *

female: 61.54 %
male: 38.46 %

What is the age of people who have Reflux oesophagitis when taking Vasotec? *

What are other drugs people take besides Vasotec? *

What are other side effects people have besides Reflux oesophagitis? *

Chest Pain: 7 people, 53.85%
Headache (pain in head): 5 people, 38.46%
Stable Angina (a constant chest pain): 5 people, 38.46%
Angina Unstable (chest pain due to ischemia of the heart muscle- unstable): 5 people, 38.46%
Dyspnea (difficult or laboured breathing): 5 people, 38.46%
Depression: 4 people, 30.77%
Diarrhea: 4 people, 30.77%
Myopathy (a muscular disease in which the muscle fibres do not function): 4 people, 30.77%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 4 people, 30.77%
Blood Creatine Phosphokinase Increased: 4 people, 30.77%

What are the existing conditions these people have? *

Wound: 2 people, 15.38%
Oedema (fluid collection in tissue): 2 people, 15.38%
Birth Control: 2 people, 15.38%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 15.38%
Depression: 2 people, 15.38%
Diabetes: 2 people, 15.38%
Heart Attack: 2 people, 15.38%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 15.38%
Type 2 Diabetes: 2 people, 15.38%
Acne (skin problems that cause pimples): 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

Do you take Vasotec and have Reflux oesophagitis?

- Check whether Reflux oesophagitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vasotec:

Vasotec (14,646 reports)

Browse all side effects of Vasotec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Reflux oesophagitis:

Reflux oesophagitis (338 drugs)

Browse all the conditions that are associated with Reflux oesophagitis:

Reflux oesophagitis (570 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on enalapril maleate (the active ingredients of Vasotec) and Vasotec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.