Velcade and Aggression aggravated - a phase IV clinical study of FDA data

Summary:

Aggression aggravated is reported as a side effect among people who take Velcade (bortezomib), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Dexamethasone, and have Encephalitis autoimmune.

The phase IV clinical study analyzes which people have Aggression aggravated when taking Velcade. It is created by eHealthMe based on reports of 66,250 people who have side effects when taking Velcade from the FDA, and is updated regularly.

What is Velcade?

Velcade has active ingredients of bortezomib. It is often used in multiple myeloma. eHealthMe is studying from 66,422 Velcade users. Check the latest studies of Velcade.

What is Aggression aggravated?

Aggression aggravated is found to be associated with 1,361 drugs and 664 conditions by eHealthMe. Check the latest studies of Aggression aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

66,250 people reported to have side effects when taking Velcade.
Among them, 53 people (0.08%) have Aggression aggravated.

Could Velcade cause Aggression aggravated?

Among these 53 people:

How long have people been on Velcade when they have Aggression aggravated? *

What is the gender of people who have Aggression aggravated when taking Velcade? *

female: 55.81 %
male: 44.19 %

What is the age of people who have Aggression aggravated when taking Velcade? *

What are other drugs people take besides Velcade? *

Dexamethasone: 20 people, 37.74%
Revlimid: 19 people, 35.85%
Darzalex: 16 people, 30.19%
Carfilzomib: 13 people, 24.53%
Cyclophosphamide: 13 people, 24.53%
Cisplatin: 13 people, 24.53%
Doxorubicin Hydrochloride: 10 people, 18.87%
Acyclovir: 9 people, 16.98%
Venclexta: 9 people, 16.98%
Etoposide: 7 people, 13.21%

What are other side effects people have besides Aggression aggravated? *

Confusional State: 19 people, 35.85%
Acute Kidney Failure: 16 people, 30.19%
Septic Shock (shock due to blood infection): 16 people, 30.19%
Blood Calcium Increased: 15 people, 28.30%
Fever: 15 people, 28.30%
Urinary Tract Infection: 15 people, 28.30%
Rebound Effect (take-back effect): 14 people, 26.42%
Therapeutic Response Unexpected: 14 people, 26.42%
Breathing-Related Sleep Disorder: 14 people, 26.42%
Cellulitis (infection under the skin): 14 people, 26.42%

What are the existing conditions these people have? *

Encephalitis Autoimmune (autoimmune origin disturbances of consciousness and pyramidal signs, inflammation of the brain): 14 people, 26.42%
Encephalitis (inflammation of the brain): 13 people, 24.53%
Immunodeficiency Disorders: 9 people, 16.98%
Light Chain Disease (a rare blood cell disease which is characterized by deposition of fragments of infection-fighting immunoglobulins): 8 people, 15.09%
Pain: 3 people, 5.66%
Plasmacytoma (neoplasm of plasma cells (usually in bone marrow)): 2 people, 3.77%
Depression: 2 people, 3.77%
Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 1 person, 1.89%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 1.89%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 1.89%

* Approximation only. Some reports may have incomplete information.

Do you take Velcade and have Aggression aggravated?

- Check whether Aggression aggravated is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Velcade:

Velcade (66,422 reports)

Browse all side effects of Velcade:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aggression aggravated:

Aggression aggravated (1,361 drugs)

Browse all the conditions that are associated with Aggression aggravated:

Aggression aggravated (664 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on bortezomib (the active ingredients of Velcade) and Velcade (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.