Venclexta and Alanine aminotransferase increased - a phase IV clinical study of FDA data

Summary:

Alanine aminotransferase increased is reported as a side effect among people who take Venclexta (venetoclax), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Azacitidine, and have Acute myeloid leukaemia.

The phase IV clinical study analyzes which people have Alanine aminotransferase increased when taking Venclexta. It is created by eHealthMe based on reports of 31,417 people who have side effects when taking Venclexta from the FDA, and is updated regularly.

What is Venclexta?

Venclexta has active ingredients of venetoclax. eHealthMe is studying from 31,425 Venclexta users. Check the latest studies of Venclexta.

What is Alanine aminotransferase increased?

Alanine aminotransferase increased is found to be associated with 2,161 drugs and 3,307 conditions by eHealthMe. Check the latest studies of Alanine aminotransferase increased.

On Jul, 14, 2026

31,417 people reported to have side effects when taking Venclexta.
Among them, 39 people (0.12%) have Alanine aminotransferase increased.

Could Venclexta cause Alanine aminotransferase increased?

Among these 39 people:

How long have people been on Venclexta when they have Alanine aminotransferase increased? *

What is the gender of people who have Alanine aminotransferase increased when taking Venclexta? *

female: 56.41 %
male: 43.59 %

What is the age of people who have Alanine aminotransferase increased when taking Venclexta? *

What are other drugs people take besides Venclexta? *

What are other side effects people have besides Alanine aminotransferase increased? *

Aspartate Aminotransferase Increased: 28 people, 71.79%
Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 10 people, 25.64%
Diarrhea: 9 people, 23.08%
White Blood Cell Count Decreased: 8 people, 20.51%
Thrombocytopenia (decrease of platelets in blood): 7 people, 17.95%
Pneumonia: 7 people, 17.95%
Hepatic Function Abnormal: 7 people, 17.95%
Fever: 7 people, 17.95%
Blood Glucose Increased: 6 people, 15.38%
Blood Alkaline Phosphatase Increased: 5 people, 12.82%

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 17 people, 43.59%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 12 people, 30.77%
Burkitt Lymphoma (cancer of the lymphatic system): 5 people, 12.82%
High Blood Pressure: 4 people, 10.26%
Anaemia Of Chronic Disease: 3 people, 7.69%
B-Cell Small Lymphocytic Lymphoma (blood cancer affecting b cells): 3 people, 7.69%
Bleeding Disorders: 3 people, 7.69%
Lymphocytic Leukaemia (a type of cancer in which the bone marrow makes too many lymphocytes): 3 people, 7.69%
Epstein-Barr Virus Infection: 3 people, 7.69%
Purpura (purplish discoloration of the skin): 3 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Venclexta and have Alanine aminotransferase increased?

- Check whether Alanine aminotransferase increased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Venclexta:

Venclexta (31,425 reports)

Browse all side effects of Venclexta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Alanine aminotransferase increased:

Alanine aminotransferase increased (2,161 drugs)

Browse all the conditions that are associated with Alanine aminotransferase increased:

Alanine aminotransferase increased (3,307 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on venetoclax (the active ingredients of Venclexta) and Venclexta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.