Venclexta and Sciatica - a phase IV clinical study of FDA data

Summary:

Sciatica is reported as a side effect among people who take Venclexta (venetoclax), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Gabapentin, and have Chronic lymphocytic leukaemia.

The phase IV clinical study analyzes which people have Sciatica when taking Venclexta. It is created by eHealthMe based on reports of 31,417 people who have side effects when taking Venclexta from the FDA, and is updated regularly.

What is Venclexta?

Venclexta has active ingredients of venetoclax. eHealthMe is studying from 31,425 Venclexta users. Check the latest studies of Venclexta.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,145 drugs and 1,423 conditions by eHealthMe. Check the latest studies of Sciatica.

On Jan, 21, 2026

31,417 people reported to have side effects when taking Venclexta.
Among them, 21 people (0.07%) have Sciatica.

Among these 21 people:

How long have people been on Venclexta when they have Sciatica? *

What is the gender of people who have Sciatica when taking Venclexta? *

female: 47.62 %
male: 52.38 %

What is the age of people who have Sciatica when taking Venclexta? *

What are other drugs people take besides Venclexta? *

What are other side effects people have besides Sciatica? *

Diarrhea: 9 people, 42.86%
Fatigue (feeling of tiredness): 7 people, 33.33%
Weakness: 6 people, 28.57%
Constipation: 4 people, 19.05%
Head Injury: 4 people, 19.05%
Neutrophil Count Increased (excess than normal number of neutrophil a type of blood cell): 4 people, 19.05%
Nausea (feeling of having an urge to vomit): 4 people, 19.05%
Discomfort: 4 people, 19.05%
Haemoglobin Decreased: 4 people, 19.05%
Joint Pain: 4 people, 19.05%

What are the existing conditions these people have? *

Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 15 people, 71.43%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 14.29%
High Blood Cholesterol: 2 people, 9.52%
Sciatic Nerve Neuropathy (sciatic nerve damage): 1 person, 4.76%
Heart Rate Irregular: 1 person, 4.76%
B-Cell Small Lymphocytic Lymphoma (blood cancer affecting b cells): 1 person, 4.76%
Bacterial Infection: 1 person, 4.76%
Cardiac Disorder: 1 person, 4.76%
Thrombocytopenia (decrease of platelets in blood): 1 person, 4.76%
Depression: 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Venclexta and have Sciatica?

- Check whether Sciatica is associated with a drug or a condition (FREE)
- Predict drug outcomes for up to one year with AI (FREE)
- Get an AI agent to monitor your drugs continuously (FREE)

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Venclexta:

Venclexta (31,425 reports)

Sciatica treatments and more:

Sciatica (28,508 reports)

Browse all side effects of Venclexta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica:

Sciatica (1,145 drugs)

Browse all the conditions that are associated with Sciatica:

Sciatica (1,423 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on venetoclax (the active ingredients of Venclexta) and Venclexta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.