Versed and Respiratory depression - a phase IV clinical study of FDA data

Summary:

Respiratory depression is reported as a side effect among people who take Versed (midazolam hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Fentanyl, and have Pain.

The phase IV clinical study analyzes which people have Respiratory depression when taking Versed. It is created by eHealthMe based on reports of 6,758 people who have side effects when taking Versed from the FDA, and is updated regularly.

What is Versed?

Versed has active ingredients of midazolam hydrochloride. It is often used in sedation during medical procedure. eHealthMe is studying from 6,869 Versed users. Check the latest studies of Versed.

What is Respiratory depression?

Respiratory depression (respiration has a rate below 12 breaths) is found to be associated with 710 drugs and 838 conditions by eHealthMe. Check the latest studies of Respiratory depression.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

6,758 people reported to have side effects when taking Versed.
Among them, 58 people (0.86%) have Respiratory depression.

Could Versed cause Respiratory depression?

Among these 58 people:

How long have people been on Versed when they have Respiratory depression? *

What is the gender of people who have Respiratory depression when taking Versed? *

female: 61.11 %
male: 38.89 %

What is the age of people who have Respiratory depression when taking Versed? *

What are other drugs people take besides Versed? *

What are other side effects people have besides Respiratory depression? *

Hypotension (abnormally low blood pressure): 10 people, 17.24%
Sedation: 8 people, 13.79%
Oxygen Saturation Decreased: 7 people, 12.07%
Loss Of Consciousness: 5 people, 8.62%
Hypoventilation (too shallow or too slow breathing, which does not meet the needs of the body): 5 people, 8.62%
Mydriasis (a dilation of the pupil): 4 people, 6.90%
Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 4 people, 6.90%
Leukocytosis (increased white blood cells): 3 people, 5.17%
Confusion: 3 people, 5.17%
Nausea (feeling of having an urge to vomit): 3 people, 5.17%

What are the existing conditions these people have? *

Pain: 7 people, 12.07%
Sedation: 6 people, 10.34%
Haemolytic Anaemia (anaemia due to haemolysis): 3 people, 5.17%
Fungal Infection: 3 people, 5.17%
Anaesthesia: 3 people, 5.17%
Procedural Pain: 2 people, 3.45%
Percutaneous Coronary Intervention: 2 people, 3.45%
Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 1 person, 1.72%
Poisoning: 1 person, 1.72%

* Approximation only. Some reports may have incomplete information.

Do you take Versed and have Respiratory depression?

- Check whether Respiratory depression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Versed:

Versed (6,869 reports)

Browse all side effects of Versed:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Respiratory depression:

Respiratory depression (710 drugs)

Browse all the conditions that are associated with Respiratory depression:

Respiratory depression (838 conditions)

Related publications that referenced our studies

Souki F, Shettar SS, "Prolonged respiratory depression after general anesthesia in an adult with congenital rubella syndrome", A&A Case Reports, 2013 Nov .
Souki F, Shettar SS, "Prolonged respiratory depression after general anesthesia in an adult with congenital rubella syndrome", A&A Case Reports, 2013 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on midazolam hydrochloride (the active ingredients of Versed) and Versed (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.