Vfend and Oedema - a phase IV clinical study of FDA data

Summary:

Oedema is reported as a side effect among people who take Vfend (voriconazole), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Lasix, and have Acute lymphocytic leukemia (all).

The phase IV clinical study analyzes which people have Oedema when taking Vfend. It is created by eHealthMe based on reports of 12,081 people who have side effects when taking Vfend from the FDA, and is updated regularly.

What is Vfend?

Vfend has active ingredients of voriconazole. It is often used in aspergillosis. eHealthMe is studying from 12,128 Vfend users. Check the latest studies of Vfend.

What is Oedema?

Oedema (fluid collection in tissue) is found to be associated with 2,188 drugs and 2,311 conditions by eHealthMe. Check the latest studies of Oedema.



On Jul, 20, 2026

12,081 people reported to have side effects when taking Vfend.
Among them, 98 people (0.81%) have Oedema.

Could Vfend cause Oedema?

Among these 98 people:

How long have people been on Vfend when they have Oedema? *

  • < 1 month: 81.4 %
  • 1 - 6 months: 16.28 %
  • 6 - 12 months: 2.33 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Oedema when taking Vfend? *

  • female: 48.39 %
  • male: 51.61 %

What is the age of people who have Oedema when taking Vfend? *

  • 0-1: 0.0 %
  • 2-9: 7.41 %
  • 10-19: 2.47 %
  • 20-29: 11.11 %
  • 30-39: 3.7 %
  • 40-49: 6.17 %
  • 50-59: 22.22 %
  • 60+: 46.91 %

What are other drugs people take besides Vfend? *

  1. Lasix: 17 people, 17.35%
  2. Vancomycin: 13 people, 13.27%
  3. Flagyl: 12 people, 12.24%
  4. Solu-Cortef: 11 people, 11.22%
  5. Prednisolone: 10 people, 10.20%
  6. Zosyn: 9 people, 9.18%
  7. Keppra: 9 people, 9.18%
  8. Prograf: 9 people, 9.18%
  9. Heparin: 8 people, 8.16%
  10. Ambisome: 7 people, 7.14%

What are other side effects people have besides Oedema? *

  1. Thrombocytopenia (decrease of platelets in blood): 17 people, 17.35%
  2. Pneumonia: 16 people, 16.33%
  3. Sepsis (a severe blood infection that can lead to organ failure and death): 15 people, 15.31%
  4. Pleural Effusion (water on the lungs): 14 people, 14.29%
  5. Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 13 people, 13.27%
  6. Fever: 13 people, 13.27%
  7. Diarrhea: 12 people, 12.24%
  8. Nausea (feeling of having an urge to vomit): 11 people, 11.22%
  9. Febrile Neutropenia (fever with reduced white blood cells): 11 people, 11.22%
  10. Weight Increased: 9 people, 9.18%

What are the existing conditions these people have? *

  1. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 13 people, 13.27%
  2. High Blood Pressure: 10 people, 10.20%
  3. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 9 people, 9.18%
  4. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 6 people, 6.12%
  5. Enlarged Prostate: 5 people, 5.10%
  6. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 5 people, 5.10%
  7. Insomnia (sleeplessness): 5 people, 5.10%
  8. Otitis (ear infection): 5 people, 5.10%
  9. Fungal Infection: 5 people, 5.10%
  10. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 5 people, 5.10%

* Approximation only. Some reports may have incomplete information.

Do you take Vfend and have Oedema?

- Check whether Oedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vfend:

Oedema treatments and more:

How severe was Oedema and when was it recovered:

Expand to all the drugs that have ingredients of voriconazole:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vfend:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Oedema:

Browse all the conditions that are associated with Oedema:


How the study uses the data?

The study uses data from the FDA. It is based on voriconazole (the active ingredients of Vfend) and Vfend (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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