Vfend and Purpura - a phase IV clinical study of FDA data
Summary:
Purpura is reported as a side effect among people who take Vfend (voriconazole), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Vancomycin, and have Primary myelofibrosis.
The phase IV clinical study analyzes which people have Purpura when taking Vfend. It is created by eHealthMe based on reports of 12,081 people who have side effects when taking Vfend from the FDA, and is updated regularly.
What is Vfend?
Vfend has active ingredients of voriconazole. It is often used in aspergillosis. eHealthMe is studying from 12,128 Vfend users. Check the latest studies of Vfend.
What is Purpura?
Purpura (purplish discoloration of the skin) is found to be associated with 938 drugs and 1,517 conditions by eHealthMe. Check the latest studies of Purpura.
12,081 people reported to have side effects when taking Vfend.
Among them, 21 people (0.17%) have Purpura.

Among these 21 people:
How long have people been on Vfend when they have Purpura? *
- < 1 month: 100 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Purpura when taking Vfend? *
- female: 37.5 %
- male: 62.5 %
What is the age of people who have Purpura when taking Vfend? *
- 0-1: 6.25 %
- 2-9: 18.75 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 6.25 %
- 40-49: 0.0 %
- 50-59: 6.25 %
- 60+: 62.5 %
What are other drugs people take besides Vfend? *
- Zyvox: 5 people, 23.81%
- Vancomycin: 5 people, 23.81%
- Jadenu: 4 people, 19.05%
- Lasix: 4 people, 19.05%
- Zocor: 3 people, 14.29%
- Zoloft: 3 people, 14.29%
- Maxipime: 3 people, 14.29%
- Vecuronium Bromide: 2 people, 9.52%
- Methylprednisolone Sodium Succinate: 2 people, 9.52%
- Bactrim: 2 people, 9.52%
What are other side effects people have besides Purpura? *
- Thrombocytopenia (decrease of platelets in blood): 12 people, 57.14%
- White Blood Cell Count Increased: 6 people, 28.57%
- White Blood Cell Count Decreased: 6 people, 28.57%
- Liver Disorder (liver diseases): 6 people, 28.57%
- Malignant Neoplasm Progression (cancer tumour came back): 6 people, 28.57%
- Acute Biphenotypic Leukaemia (leukaemia where the lineage is of both lymphoid and myeloid origin): 6 people, 28.57%
- Pneumonia: 5 people, 23.81%
- Melaena (the passage of black, tarry stools): 5 people, 23.81%
- Leukaemic Infiltration Pulmonary (cancer cells of white blood cells affects lungs): 4 people, 19.05%
- Hepatomegaly (abnormal enlargement of the liver): 3 people, 14.29%
What are the existing conditions these people have? *
- Primary Myelofibrosis (primary disorder of the bone marrow): 6 people, 28.57%
- Pneumonia Staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus): 3 people, 14.29%
- Anaemia (lack of blood): 3 people, 14.29%
- Iron Overload: 2 people, 9.52%
- Fungal Infection: 2 people, 9.52%
- Thrombocytopenia (decrease of platelets in blood): 1 person, 4.76%
- Still's Disease Adult Onset (a rare illness that causes high fevers, rash, and joint pain in adult just started): 1 person, 4.76%
- Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid): 1 person, 4.76%
- Febrile Neutropenia (fever with reduced white blood cells): 1 person, 4.76%
- Endocarditis Candida (an inflammation of the inner layer of the heart by infection by fungi): 1 person, 4.76%
* Approximation only. Some reports may have incomplete information.
Do you take Vfend and have Purpura?
- Check whether Purpura is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Vfend:
- Vfend (12,128 reports)
Purpura treatments and more:
- Purpura (10,762 reports)
How severe was Purpura and when was it recovered:
Expand to all the drugs that have ingredients of voriconazole:
- Purpura and drugs with ingredients of voriconazole (41 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Vfend:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Purpura:
- Purpura (938 drugs)
Browse all the conditions that are associated with Purpura:
- Purpura (1,517 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on voriconazole (the active ingredients of Vfend) and Vfend (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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