Vfend and Skin reaction - a phase IV clinical study of FDA data

Summary:

Skin reaction is reported as a side effect among people who take Vfend (voriconazole), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Diflucan, and have Chronic obstructive pulmonary disease.

The phase IV clinical study analyzes which people have Skin reaction when taking Vfend. It is created by eHealthMe based on reports of 12,081 people who have side effects when taking Vfend from the FDA, and is updated regularly.

What is Vfend?

Vfend has active ingredients of voriconazole. It is often used in aspergillosis. eHealthMe is studying from 12,128 Vfend users. Check the latest studies of Vfend.

What is Skin reaction?

Skin reaction is found to be associated with 769 drugs and 899 conditions by eHealthMe. Check the latest studies of Skin reaction.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

12,081 people reported to have side effects when taking Vfend.
Among them, 14 people (0.12%) have Skin reaction.

Could Vfend cause Skin reaction?

Among these 14 people:

How long have people been on Vfend when they have Skin reaction? *

  • < 1 month: 20 %
  • 1 - 6 months: 80 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Skin reaction when taking Vfend? *

  • female: 0.0 %
  • male: 100 %

What is the age of people who have Skin reaction when taking Vfend? *

  • 0-1: 10 %
  • 2-9: 10 %
  • 10-19: 20 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 20 %
  • 50-59: 0.0 %
  • 60+: 40 %

What are other drugs people take besides Vfend? *

  1. Diflucan: 2 people, 14.29%
  2. Videx Ec: 1 person, 7.14%
  3. Temazepam: 1 person, 7.14%
  4. Prednisolone: 1 person, 7.14%
  5. Posaconazole: 1 person, 7.14%
  6. Pantoprazole: 1 person, 7.14%
  7. Norvir: 1 person, 7.14%
  8. Neupogen: 1 person, 7.14%
  9. Losartan: 1 person, 7.14%
  10. Leucovorin Calcium: 1 person, 7.14%

What are other side effects people have besides Skin reaction? *

  1. Rashes (redness): 6 people, 42.86%
  2. Urticaria (rash of round, red welts on the skin that itch intensely): 3 people, 21.43%
  3. Photosensitivity Reaction: 3 people, 21.43%
  4. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 3 people, 21.43%
  5. Lip Oedema (swelling of lip): 2 people, 14.29%
  6. Skin Nodule (slightly elevated lesions on or in the skin): 1 person, 7.14%
  7. Bone Marrow Failure: 1 person, 7.14%
  8. Cartilage Injury: 1 person, 7.14%
  9. Coughing Up Blood: 1 person, 7.14%
  10. Dermatitis Exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss): 1 person, 7.14%

What are the existing conditions these people have? *

  1. Mycobacterium Avium Complex Infection: 3 people, 21.43%
  2. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 21.43%
  3. Fungal Infection: 2 people, 14.29%
  4. Pulmonary Aspergilloma (Mycetoma) (mass caused by a fungal infection that usually grows in lung): 1 person, 7.14%
  5. Pain: 1 person, 7.14%
  6. Liver Disorder (liver diseases): 1 person, 7.14%
  7. Ill-Defined Disorder: 1 person, 7.14%
  8. High Blood Pressure: 1 person, 7.14%
  9. Coccidioidomycosis (serious disease of the lungs and other tissues, caused by the fungus coccidioides immitis): 1 person, 7.14%
  10. Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Vfend and have Skin reaction?

- Check whether Skin reaction is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vfend:

Skin reaction treatments and more:

How severe was Skin reaction and when was it recovered:

Expand to all the drugs that have ingredients of voriconazole:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vfend:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Skin reaction:

Browse all the conditions that are associated with Skin reaction:


How the study uses the data?

The study uses data from the FDA. It is based on voriconazole (the active ingredients of Vfend) and Vfend (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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